Literature DB >> 20097484

Measurement of neutron dose equivalent and its dependence on beam configuration for a passive scattering proton delivery system.

Xin Wang1, Narayan Sahoo, Ronald X Zhu, John R Zullo, Michael T Gillin.   

Abstract

PURPOSE: To measure the neutron dose equivalent per therapeutic proton dose (H/D) in a passive scattering proton therapy system and study its dependence on the proton energy, aperture-to-isocenter distance, spread-out Bragg peak (SOBP) width, and field size. METHODS AND MATERIALS: We performed four experiments of varying proton energies, aperture-to-isocenter distances, SOBP widths, and field sizes. Etched track detectors were used to measure the neutron dose equivalent at both an in-field (isocenter, beyond the protons' range) and out-of-field (30 cm lateral to the isocenter) location in air.
RESULTS: For a nonmodulated beam with all the protons stopping in the aperture and an aperture-to-isocenter distance of 30 cm, the H/D values measured at the isocenter were approximately 0.3 mSv/Gy for all snouts with a 100-MeV beam. The H/D values increased to 10.7, 14.5, and 15.1 mSv/Gy, respectively, for small, medium, and large snouts when the beam energy increased to 250 MeV. At the out-of-field location, H/D values increased from 0.1 to 2.7, 3.0, and 3.2 mSv/Gy, respectively, for small, medium, and large snouts. When the aperture-to-isocenter distance was changed from 10 to 40 cm, the H/D value at the isocenter dropped 70%. The H/D value doubled for the modulated beam relative to the nonmodulated beam. Open apertures reduced the neutrons produced in the nozzle, but increased those produced in the phantom.
CONCLUSIONS: Our data showed that changes in the four factors studied affect the H/D value in predictable ways which permits an estimate of a patient's neutron exposure.

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Year:  2010        PMID: 20097484     DOI: 10.1016/j.ijrobp.2009.07.1732

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN: 0360-3016            Impact factor:   7.038


  3 in total

1.  Secondary neutron spectrum from 250-MeV passively scattered proton therapy: measurement with an extended-range Bonner sphere system.

Authors:  Rebecca M Howell; E A Burgett
Journal:  Med Phys       Date:  2014-09       Impact factor: 4.071

2.  Malfunctions of implantable cardiac devices in patients receiving proton beam therapy: incidence and predictors.

Authors:  Daniel R Gomez; Falk Poenisch; Chelsea C Pinnix; Tommy Sheu; Joe Y Chang; Nada Memon; Radhe Mohan; Marc A Rozner; Anne H Dougherty
Journal:  Int J Radiat Oncol Biol Phys       Date:  2013-11-01       Impact factor: 7.038

3.  Spot scanning proton therapy minimizes neutron dose in the setting of radiation therapy administered during pregnancy.

Authors:  Xin Wang; Falk Poenisch; Narayan Sahoo; Ronald X Zhu; MingFwu Lii; Michael T Gillin; Jing Li; David Grosshans
Journal:  J Appl Clin Med Phys       Date:  2016-09-08       Impact factor: 2.102

  3 in total

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