Literature DB >> 20090205

Induced pluripotent stem cells for retinal degenerative diseases: a new perspective on the challenges.

Zi-Bing Jin1, Satoshi Okamoto, Michiko Mandai, Masayo Takahashi.   

Abstract

Retinal degenerative diseases, including age-related macular degeneration and retinitis pigmentosa, are the prodominant causes of human blindness in the world; however, these diseases are difficult to treat. Currently, knowledge on the mechanisms of these diseases is still very limited and no radical drugs are available. Induced pluripotent stem (iPS) cells are an innovative technology that turns somatic cells into embryonic stem (ES)-like cells with pluripotent potential via the exogenous expression of several key genes. It can be used as an unlimited source for cell differentiation or tissue engineering, either of which is a promising therapy for human degenerative diseases. Induced pluripotent cells are both an unlimited source for retinal regeneration and an expectant tool for pharmaprojects and developmental or disease modelling. In this review, we try to summarize the advancement of iPS-based technologies and the potential utility for retinal degenerative diseases. We also discuss the challenges of using this technology in the retinology field.

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Mesh：

Year:  2009        PMID： 20090205     DOI： 10.1007/s12041-009-0063-5

Source DB:  PubMed          Journal:  J Genet        ISSN： 0022-1333            Impact factor:   1.166


  59 in total

1.  Macular pigment and lutein supplementation in retinitis pigmentosa and Usher syndrome.

Authors:  T S Aleman; J L Duncan; M L Bieber; E de Castro; D A Marks; L M Gardner; J D Steinberg; A V Cideciyan; M G Maguire; S G Jacobson
Journal:  Invest Ophthalmol Vis Sci       Date:  2001-07       Impact factor: 4.799

2.  HLA-haplotype banking and iPS cells.

Authors:  Norio Nakatsuji; Fumiaki Nakajima; Katsushi Tokunaga
Journal:  Nat Biotechnol       Date:  2008-07       Impact factor: 54.908

3.  In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction.

Authors:  Fumitaka Osakada; Zi-Bing Jin; Yasuhiko Hirami; Hanako Ikeda; Teruko Danjyo; Kiichi Watanabe; Yoshiki Sasai; Masayo Takahashi
Journal:  J Cell Sci       Date:  2009-08-11       Impact factor: 5.285

4.  Restoration of photoreceptor ultrastructure and function in retinal degeneration slow mice by gene therapy.

Authors:  R R Ali; G M Sarra; C Stephens; M D Alwis; J W Bainbridge; P M Munro; S Fauser; M B Reichel; C Kinnon; D M Hunt; S S Bhattacharya; A J Thrasher
Journal:  Nat Genet       Date:  2000-07       Impact factor: 38.330

5.  Human neural retinal transplantation.

Authors:  M S Humayun; E de Juan; M del Cerro; G Dagnelie; W Radner; S R Sadda; C del Cerro
Journal:  Invest Ophthalmol Vis Sci       Date:  2000-09       Impact factor: 4.799

6.  Induced pluripotent stem cells offer new approach to therapy in thalassemia and sickle cell anemia and option in prenatal diagnosis in genetic diseases.

Authors:  Lin Ye; Judy C Chang; Chin Lin; Xiaofang Sun; Jingwei Yu; Yuet Wai Kan
Journal:  Proc Natl Acad Sci U S A       Date:  2009-05-29       Impact factor: 11.205

7.  Embryonic stem cell-specific microRNAs promote induced pluripotency.

Authors:  Robert L Judson; Joshua E Babiarz; Monica Venere; Robert Blelloch
Journal:  Nat Biotechnol       Date:  2009-04-12       Impact factor: 54.908

Review 8.  Induced pluripotent stem cells: current progress and potential for regenerative medicine.

Authors:  Giovanni Amabile; Alexander Meissner
Journal:  Trends Mol Med       Date:  2009-01-21       Impact factor: 11.951

9.  Retinal repair by transplantation of photoreceptor precursors.

Authors:  R E MacLaren; R A Pearson; A MacNeil; R H Douglas; T E Salt; M Akimoto; A Swaroop; J C Sowden; R R Ali
Journal:  Nature       Date:  2006-11-09       Impact factor: 49.962

Review 10.  Potential application of embryonic stem cells in Parkinson's disease: drug screening and cell therapy.

Authors:  Hsin-Yi Ho; Meng Li
Journal:  Regen Med       Date:  2006-03       Impact factor: 3.806
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  26 in total

Review 1.  De novo myocardial regeneration: advances and pitfalls.

Authors:  Khawaja Husnain Haider; Stephanie Buccini; Rafeeq P H Ahmed; Muhammad Ashraf
Journal:  Antioxid Redox Signal       Date:  2010-10-12       Impact factor: 8.401

2.  Differentiation of induced pluripotent stem cells of swine into rod photoreceptors and their integration into the retina.

Authors:  Liang Zhou; Wei Wang; Yongqing Liu; Juan Fernandez de Castro; Toshihiko Ezashi; Bhanu Prakash V L Telugu; R Michael Roberts; Henry J Kaplan; Douglas C Dean
Journal:  Stem Cells       Date:  2011-06       Impact factor: 6.277

3.  Insights from Genetic Model Systems of Retinal Degeneration: Role of Epsins in Retinal Angiogenesis and VEGFR2 Signaling.

Authors:  Yunzhou Dong; Xue Cai; Yong Wu; Yanjun Liu; Lin Deng; Hong Chen
Journal:  J Nat Sci       Date:  2017-01

Review 4.  Induced pluripotent stem cell therapies for geographic atrophy of age-related macular degeneration.

Authors:  Hongjun Du; Siok Lam Lim; Seanna Grob; Kang Zhang
Journal:  Semin Ophthalmol       Date:  2011-05       Impact factor: 1.975

5.  Shaping the eye from embryonic stem cells: Biological and medical implications.

Authors:  Gabriele Colozza; Morgane Locker; Muriel Perron
Journal:  World J Stem Cells       Date:  2012-08-26       Impact factor: 5.326

Review 6.  Stem cell-based therapies for age-related macular degeneration: current status and prospects.

Authors:  Yalin Mu; Manli Zhao; Guangming Su
Journal:  Int J Clin Exp Med       Date:  2014-11-15

Review 7.  Cloning of non-human primates: the road "less traveled by".

Authors:  Michelle L Sparman; Masahito Tachibana; Shoukhrat M Mitalipov
Journal:  Int J Dev Biol       Date:  2010       Impact factor: 2.203

Review 8.  Translating induced pluripotent stem cells from bench to bedside: application to retinal diseases.

Authors:  Alona O Cramer; Robert E MacLaren
Journal:  Curr Gene Ther       Date:  2013-04       Impact factor: 4.391

9.  Treatment of massive subretinal hematoma associated with age-related macular degeneration using vitrectomy with intentional giant tear.

Authors:  Eisuke Isizaki; Seita Morishita; Takaki Sato; Masanori Fukumoto; Hiroyuki Suzuki; Teruyo Kida; Mari Ueki; Tsunehiko Ikeda
Journal:  Int Ophthalmol       Date:  2015-07-28       Impact factor: 2.031

Review 10.  Retinal Tissue Bioengineering, Materials and Methods for the Treatment of Glaucoma.

Authors:  Sanaz Behtaj; Andreas Öchsner; Yuri G Anissimov; Maksym Rybachuk
Journal:  Tissue Eng Regen Med       Date:  2020-05-10       Impact factor: 4.169
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