Literature DB >> 19363475

Embryonic stem cell-specific microRNAs promote induced pluripotency.

Robert L Judson1, Joshua E Babiarz, Monica Venere, Robert Blelloch.   

Abstract

This report demonstrates that introduction of microRNAs (miRNAs) specific to embryonic stem cells enhances the production of mouse induced pluripotent stem (iPS) cells. The miRNAs miR-291-3p, miR-294 and miR-295 increase the efficiency of reprogramming by Oct4, Sox2 and Klf4, but not by these factors plus cMyc. cMyc binds the promoter of the miRNAs, suggesting that they are downstream effectors of cMyc during reprogramming. However, unlike cMyc, the miRNAs induce a homogeneous population of iPS cell colonies.

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Year:  2009        PMID： 19363475      PMCID： PMC2743930          DOI： 10.1038/nbt.1535

Source DB:  PubMed          Journal:  Nat Biotechnol        ISSN： 1087-0156            Impact factor:   54.908


  16 in total

1.  Embryonic stem cell-specific MicroRNAs.

Authors:  Hristo B Houbaviy; Michael F Murray; Phillip A Sharp
Journal:  Dev Cell       Date:  2003-08       Impact factor: 12.270

Review 2.  Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation.

Authors:  Keith W Orford; David T Scadden
Journal:  Nat Rev Genet       Date:  2008-02       Impact factor: 53.242

3.  Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse.

Authors:  Matthias Stadtfeld; Nimet Maherali; David T Breault; Konrad Hochedlinger
Journal:  Cell Stem Cell       Date:  2008-02-14       Impact factor: 24.633

4.  A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors.

Authors:  P Mathijs Voorhoeve; Carlos le Sage; Mariette Schrier; Ad J M Gillis; Hans Stoop; Remco Nagel; Ying-Poi Liu; Josyanne van Duijse; Jarno Drost; Alexander Griekspoor; Eitan Zlotorynski; Norikazu Yabuta; Gabriella De Vita; Hiroshi Nojima; Leendert H J Looijenga; Reuven Agami
Journal:  Cell       Date:  2006-03-24       Impact factor: 41.582

5.  Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.

Authors:  Kazutoshi Takahashi; Shinya Yamanaka
Journal:  Cell       Date:  2006-08-10       Impact factor: 41.582

6.  Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells.

Authors:  Tobias Brambrink; Ruth Foreman; G Grant Welstead; Christopher J Lengner; Marius Wernig; Heikyung Suh; Rudolf Jaenisch
Journal:  Cell Stem Cell       Date:  2008-02-07       Impact factor: 24.633

7.  Integration of external signaling pathways with the core transcriptional network in embryonic stem cells.

Authors:  Xi Chen; Han Xu; Ping Yuan; Fang Fang; Mikael Huss; Vinsensius B Vega; Eleanor Wong; Yuriy L Orlov; Weiwei Zhang; Jianming Jiang; Yuin-Han Loh; Hock Chuan Yeo; Zhen Xuan Yeo; Vipin Narang; Kunde Ramamoorthy Govindarajan; Bernard Leong; Atif Shahab; Yijun Ruan; Guillaume Bourque; Wing-Kin Sung; Neil D Clarke; Chia-Lin Wei; Huck-Hui Ng
Journal:  Cell       Date:  2008-06-13       Impact factor: 41.582

8.  Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts.

Authors:  Masato Nakagawa; Michiyo Koyanagi; Koji Tanabe; Kazutoshi Takahashi; Tomoko Ichisaka; Takashi Aoi; Keisuke Okita; Yuji Mochiduki; Nanako Takizawa; Shinya Yamanaka
Journal:  Nat Biotechnol       Date:  2007-11-30       Impact factor: 54.908

9.  Genome-wide maps of chromatin state in pluripotent and lineage-committed cells.

Authors:  Tarjei S Mikkelsen; Manching Ku; David B Jaffe; Biju Issac; Erez Lieberman; Georgia Giannoukos; Pablo Alvarez; William Brockman; Tae-Kyung Kim; Richard P Koche; William Lee; Eric Mendenhall; Aisling O'Donovan; Aviva Presser; Carsten Russ; Xiaohui Xie; Alexander Meissner; Marius Wernig; Rudolf Jaenisch; Chad Nusbaum; Eric S Lander; Bradley E Bernstein
Journal:  Nature       Date:  2007-07-01       Impact factor: 49.962

10.  Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation.

Authors:  Yangming Wang; Scott Baskerville; Archana Shenoy; Joshua E Babiarz; Lauren Baehner; Robert Blelloch
Journal:  Nat Genet       Date:  2008-11-02       Impact factor: 38.330
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  310 in total

Review 1.  microRNAs, the cell's Nepenthe: clearing the past during the maternal-to-zygotic transition and cellular reprogramming.

Authors:  Antonio J Giraldez
Journal:  Curr Opin Genet Dev       Date:  2010-05-06       Impact factor: 5.578

Review 2.  From microRNAs to targets: pathway discovery in cell fate transitions.

Authors:  Deepa Subramanyam; Robert Blelloch
Journal:  Curr Opin Genet Dev       Date:  2011-06-01       Impact factor: 5.578

Review 3.  Nuclear reprogramming to a pluripotent state by three approaches.

Authors:  Shinya Yamanaka; Helen M Blau
Journal:  Nature       Date:  2010-06-10       Impact factor: 49.962

Review 4.  Using human pluripotent stem cells to untangle neurodegenerative disease mechanisms.

Authors:  Brigitte Malgrange; Laurence Borgs; Benjamin Grobarczyk; Audrey Purnelle; Patricia Ernst; Gustave Moonen; Laurent Nguyen
Journal:  Cell Mol Life Sci       Date:  2010-10-26       Impact factor: 9.261

Review 5.  Epigenetic landscape of pluripotent stem cells.

Authors:  Ji Woong Han; Young-sup Yoon
Journal:  Antioxid Redox Signal       Date:  2012-01-11       Impact factor: 8.401

Review 6.  MicroRNAs are shaping the hematopoietic landscape.

Authors:  Ute Bissels; Andreas Bosio; Wolfgang Wagner
Journal:  Haematologica       Date:  2011-11-04       Impact factor: 9.941

Review 7.  Mechanism and methods to induce pluripotency.

Authors:  Peizhe Wang; Jie Na
Journal:  Protein Cell       Date:  2011-11-06       Impact factor: 14.870

Review 8.  Learning the molecular mechanisms of the reprogramming factors: let's start from microRNAs.

Authors:  Chao-Shun Yang; Tariq M Rana
Journal:  Mol Biosyst       Date:  2012-10-05

Review 9.  Mechanisms underlying the formation of induced pluripotent stem cells.

Authors:  Federico González; Danwei Huangfu
Journal:  Wiley Interdiscip Rev Dev Biol       Date:  2015-09-18       Impact factor: 5.814

10.  Critical regulation of miR-200/ZEB2 pathway in Oct4/Sox2-induced mesenchymal-to-epithelial transition and induced pluripotent stem cell generation.

Authors:  Guiying Wang; Xudong Guo; Wujun Hong; Qidong Liu; Tingyi Wei; Chenqi Lu; Longfei Gao; Dan Ye; Yi Zhou; Jie Chen; Jianmin Wang; Minjuan Wu; Houqi Liu; Jiuhong Kang
Journal:  Proc Natl Acad Sci U S A       Date:  2013-02-05       Impact factor: 11.205
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