INTRODUCTION AND HYPOTHESIS: Two-year outcomes of treating cystocele with a polypropylene mesh (Perigee System with IntePro, AMS, Inc.) placed via a transobturator approach are reported. METHODS: A prospective, multicenter trial was conducted evaluating 114 women with >or= stage II anterior wall prolapse defined using International Continence Society guidelines. Treatment success was defined as anterior stage <or= I at a 24-month follow-up. Quality of life questionnaires were administered at baseline and follow-up. Complications were reported via adverse events. RESULTS: Efficacy at 24 months was 88.5% (77/87). Pelvic floor distress inventory, pelvic floor impact questionnaire-7, and pelvic organ prolapse/urinary incontinence sexual questionnaire were all significantly improved from baseline (p < 0.001). Complication rates reported were vaginal mesh extrusion 10.5% (12/114) and groin, pelvic, or vaginal pain 4.4% (5/114). Six subjects reported de novo dyspareunia. Out of the 49 subjects reporting dyspareunia at baseline, 15 were resolved postoperatively. CONCLUSIONS: The Perigee System is an effective treatment to repair anterior wall prolapse with a low rate of complications through a 2-year follow-up.
INTRODUCTION AND HYPOTHESIS: Two-year outcomes of treating cystocele with a polypropylene mesh (Perigee System with IntePro, AMS, Inc.) placed via a transobturator approach are reported. METHODS: A prospective, multicenter trial was conducted evaluating 114 women with >or= stage II anterior wall prolapse defined using International Continence Society guidelines. Treatment success was defined as anterior stage <or= I at a 24-month follow-up. Quality of life questionnaires were administered at baseline and follow-up. Complications were reported via adverse events. RESULTS: Efficacy at 24 months was 88.5% (77/87). Pelvic floor distress inventory, pelvic floor impact questionnaire-7, and pelvic organ prolapse/urinary incontinence sexual questionnaire were all significantly improved from baseline (p < 0.001). Complication rates reported were vaginal mesh extrusion 10.5% (12/114) and groin, pelvic, or vaginal pain 4.4% (5/114). Six subjects reported de novo dyspareunia. Out of the 49 subjects reporting dyspareunia at baseline, 15 were resolved postoperatively. CONCLUSIONS: The Perigee System is an effective treatment to repair anterior wall prolapse with a low rate of complications through a 2-year follow-up.
Authors: R C Bump; A Mattiasson; K Bø; L P Brubaker; J O DeLancey; P Klarskov; B L Shull; A R Smith Journal: Am J Obstet Gynecol Date: 1996-07 Impact factor: 8.661
Authors: Reijo Hiltunen; Kari Nieminen; Teuvo Takala; Eila Heiskanen; Mauri Merikari; Kirsti Niemi; Pentti K Heinonen Journal: Obstet Gynecol Date: 2007-08 Impact factor: 7.661
Authors: K Baeßler; T Aigmüller; S Albrich; C Anthuber; D Finas; T Fink; C Fünfgeld; B Gabriel; U Henscher; F H Hetzer; M Hübner; B Junginger; K Jundt; S Kropshofer; A Kuhn; L Logé; G Nauman; U Peschers; T Pfiffer; O Schwandner; A Strauss; R Tunn; V Viereck Journal: Geburtshilfe Frauenheilkd Date: 2016-12 Impact factor: 2.915