Literature DB >> 20085289

Burkholdines 1097 and 1229, potent antifungal peptides from Burkholderia ambifaria 2.2N.

Kamilia A Tawfik1, Peter Jeffs, Brian Bray, George Dubay, Joseph O Falkinham, Mostafa Mesbah, Diaa Youssef, Sherief Khalifa, Eric W Schmidt.   

Abstract

Potent antifungal cyclic lipopeptides, burkholdines (Bk), were isolated from a culture of Burkholderia ambifaria 2.2N. Bk-1229 (1) and Bk-1097 (2) are octapeptides comprised of nonproteinogenic amino acids, including beta-hydroxytyrosine, beta-hydroxyasparagine, and a new fatty acyl amino acid. 1 and 2 are fungicidal against a panel of fungi with potencies 2-60-fold better than amphotericin B control.

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Year:  2010        PMID： 20085289     DOI： 10.1021/ol9029269

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  14 in total

Review 1.  A comprehensive review of glycosylated bacterial natural products.

Authors:  Sherif I Elshahawi; Khaled A Shaaban; Madan K Kharel; Jon S Thorson
Journal:  Chem Soc Rev       Date:  2015-11-07       Impact factor: 54.564

Review 2.  Nonribosomal peptides and polyketides of Burkholderia: new compounds potentially implicated in biocontrol and pharmaceuticals.

Authors:  Qassim Esmaeel; Maude Pupin; Philippe Jacques; Valérie Leclère
Journal:  Environ Sci Pollut Res Int       Date:  2017-05-25       Impact factor: 4.223

3.  Burkholderia as a Source of Natural Products.

Authors:  Sylvia Kunakom; Alessandra S Eustáquio
Journal:  J Nat Prod       Date:  2019-07-11       Impact factor: 4.050

4.  Custom Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometric Database for Identification of Environmental Isolates of the Genus Burkholderia and Related Genera.

Authors:  Claire H Fergusson; Julienne M F Coloma; Mercia C Valentine; F P Jake Haeckl; Roger G Linington
Journal:  Appl Environ Microbiol       Date:  2020-05-19       Impact factor: 4.792

5.  Occidiofungin's chemical stability and in vitro potency against Candida species.

Authors:  Dayna Ellis; Jiten Gosai; Charles Emrick; Rachel Heintz; Lanette Romans; Donna Gordon; Shi-En Lu; Frank Austin; Leif Smith
Journal:  Antimicrob Agents Chemother       Date:  2011-11-21       Impact factor: 5.191

6.  Production of bioactive volatiles by different Burkholderia ambifaria strains.

Authors:  Ulrike Groenhagen; Rita Baumgartner; Aurélien Bailly; Amber Gardiner; Leo Eberl; Stefan Schulz; Laure Weisskopf
Journal:  J Chem Ecol       Date:  2013-07-07       Impact factor: 2.626

7.  A Burkholderia cepacia complex non-ribosomal peptide-synthesized toxin is hemolytic and required for full virulence.

Authors:  Euan L S Thomson; Jonathan J Dennis
Journal:  Virulence       Date:  2012-05-01       Impact factor: 5.882

8.  Biosynthesis of Ditropolonyl Sulfide, an Antibacterial Compound Produced by Burkholderia cepacia Complex Strain R-12632.

Authors:  Eliza Depoorter; Tom Coenye; Peter Vandamme
Journal:  Appl Environ Microbiol       Date:  2021-09-15       Impact factor: 4.792

9.  Identification of quorum sensing-controlled genes in Burkholderia ambifaria.

Authors:  Annelise Chapalain; Ludovic Vial; Natacha Laprade; Valérie Dekimpe; Jonathan Perreault; Eric Déziel
Journal:  Microbiologyopen       Date:  2013-02-05       Impact factor: 3.139

10.  Identification of volatile compounds produced by the bacterium Burkholderia tropica that inhibit the growth of fungal pathogens.

Authors:  Silvia Tenorio-Salgado; Raunel Tinoco; Rafael Vazquez-Duhalt; Jesus Caballero-Mellado; Ernesto Perez-Rueda
Journal:  Bioengineered       Date:  2013-07-02       Impact factor: 3.269
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