Literature DB >> 20057316

Impact of limited population diversity of genome-wide association studies.

Susanne B Haga1.   

Abstract

The article describes the limited population diversity of genome-wide association studies and its resulting impact on the development of commercial genetic tests with restricted applicability and usefulness to certain groups, potentially increasing existing disparities. To enable development of new clinical tools applicable to all groups, much more focus is needed to engage minority communities to enroll in genetics or genomic research studies and on investigators to reach out to underrepresented communities.

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Year:  2010        PMID: 20057316     DOI: 10.1097/GIM.0b013e3181ca2bbf

Source DB:  PubMed          Journal:  Genet Med        ISSN: 1098-3600            Impact factor:   8.822


  48 in total

1.  Attitudes Toward Return of Genetic Research Results to Relatives, Including After Death: Comparison of Cancer Probands, Blood Relatives, and Spouse/Partners.

Authors:  Carmen Radecki Breitkopf; Susan M Wolf; Kari G Chaffee; Marguerite E Robinson; Noralane M Lindor; Deborah R Gordon; Barbara A Koenig; Gloria M Petersen
Journal:  J Empir Res Hum Res Ethics       Date:  2018-04-27       Impact factor: 1.742

2.  Factors associated with willingness to provide biospecimens for genetics research among African American cancer survivors.

Authors:  Altovise T Ewing; Nnenna Kalu; Gloria Cain; Lori H Erby; Luisel J Ricks-Santi; Eva Tetteyfio-Kidd Telemaque; Denise M Scott
Journal:  J Community Genet       Date:  2019-03-14

3.  Educating Hispanics About Clinical Trials and Biobanking.

Authors:  M Lizette Rangel; Natalia I Heredia; Belinda Reininger; Lorna McNeill; Maria E Fernandez
Journal:  J Cancer Educ       Date:  2019-12       Impact factor: 2.037

Review 4.  Genome-Wide Association Studies of Chemotherapeutic Toxicities: Genomics of Inequality.

Authors:  Brandon Mapes; Omar El Charif; Shereen Al-Sawwaf; M Eileen Dolan
Journal:  Clin Cancer Res       Date:  2017-04-25       Impact factor: 12.531

5.  Community Perceptions of Biobanking Participation: A Qualitative Study among Mexican-Americans in Three Texas Cities.

Authors:  Natalia I Heredia; Sarah Krasny; Larkin L Strong; Laura Von Hatten; Lynne Nguyen; Belinda M Reininger; Lorna H McNeill; María E Fernández
Journal:  Public Health Genomics       Date:  2016-12-08       Impact factor: 2.000

Review 6.  Translating biomarkers to clinical practice.

Authors:  R H Perlis
Journal:  Mol Psychiatry       Date:  2011-06-28       Impact factor: 15.992

Review 7.  The Advantages and Challenges of Diversity in Pharmacogenomics: Can Minority Populations Bring Us Closer to Implementation?

Authors:  Honghong Zhang; Tanima De; Yizhen Zhong; Minoli A Perera
Journal:  Clin Pharmacol Ther       Date:  2019-08       Impact factor: 6.875

8.  Reasons for participating and genetic information needs among racially and ethnically diverse biobank participants: a focus group study.

Authors:  Samantha A Streicher; Saskia C Sanderson; Ethylin Wang Jabs; Michael Diefenbach; Meg Smirnoff; Inga Peter; Carol R Horowitz; Barbara Brenner; Lynne D Richardson
Journal:  J Community Genet       Date:  2011-06-07

9.  Factors Associated with African-American Women's Decisions to Participate in Genetic Research.

Authors:  Carolyn H Still; Faye A Gary; Patricia E McDonald; Hossein N Yarandi
Journal:  J Natl Black Nurses Assoc       Date:  2014-07

10.  Determining the effects and challenges of incorporating genetic testing into primary care management of hypertensive patients with African ancestry.

Authors:  C R Horowitz; N S Abul-Husn; S Ellis; M A Ramos; R Negron; M Suprun; R E Zinberg; T Sabin; D Hauser; N Calman; E Bagiella; E P Bottinger
Journal:  Contemp Clin Trials       Date:  2015-12-30       Impact factor: 2.226

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