Literature DB >> 20052971

Hydroxylated sclerosporin derivatives from the marine-derived fungus Cadophora malorum.

Celso Almeida1, Ekaterina Eguereva, Stefan Kehraus, Carsten Siering, Gabriele M König.   

Abstract

The marine-derived fungus Cadophora malorum was isolated from the green alga Enteromorpha sp. Growth on a biomalt medium supplemented with sea salt yielded an extract, from which we have isolated sclerosporin and four new hydroxylated sclerosporin derivatives, namely, 15-hydroxysclerosporin (2), 12-hydroxysclerosporin (3), 11-hydroxysclerosporin (4), and 8-hydroxysclerosporin (5). The compounds were evaluated in various biological activity assays. Compound 5 showed a weak fat-accumulation inhibitory activity against 3T3-L1 murine adipocytes.

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Year:  2010        PMID： 20052971      PMCID： PMC2846207          DOI： 10.1021/np900608d

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  10 in total

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5.  CR8, a potent and selective, roscovitine-derived inhibitor of cyclin-dependent kinases.

Authors:  K Bettayeb; N Oumata; A Echalier; Y Ferandin; J A Endicott; H Galons; L Meijer
Journal:  Oncogene       Date:  2008-06-23       Impact factor: 9.867

6.  1,2,3-Selenadiazole thioacetanilides: synthesis and anti-HIV activity evaluation.

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Authors:  Kerstin Neumann; Stefan Kehraus; Michael Gütschow; Gabriele M König
Journal:  Nat Prod Commun       Date:  2009-03       Impact factor: 0.986

9.  Tetrazolium-based colorimetric assay for the detection of HIV replication inhibitors: revisited 20 years later.

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10.  Interferon alfacon 1 inhibits SARS-CoV infection in human bronchial epithelial Calu-3 cells.

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Journal:  Biochem Biophys Res Commun       Date:  2008-04-10       Impact factor: 3.575
  10 in total
  5 in total

1.  Unconventional Cell Division Cycles from Marine-Derived Yeasts.

Authors:  Lorna M Y Mitchison-Field; José M Vargas-Muñiz; Benjamin M Stormo; Ellysa J D Vogt; Sarah Van Dierdonck; James F Pelletier; Christoph Ehrlich; Daniel J Lew; Christine M Field; Amy S Gladfelter
Journal:  Curr Biol       Date:  2019-10-10       Impact factor: 10.834

2.  Cyclic heptapeptides with metal binding properties isolated from the fungus Cadophora malorum from Antarctic soil.

Authors:  Guidmar C Donalle; María Martha Martorell; Gastón E Siless; Lucas Ruberto; Gabriela M Cabrera
Journal:  Nat Prod Bioprospect       Date:  2022-07-14

Review 3.  Terpenes from marine-derived fungi.

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Journal:  Mar Drugs       Date:  2010-08-13       Impact factor: 5.118

4.  Isolation of fungi using the diffusion chamber device FIND technology.

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5.  Differential interaction of the dark septate endophyte Cadophora sp. and fungal pathogens in vitro and in planta.

Authors:  Wael Yakti; Gábor M Kovács; Philipp Franken
Journal:  FEMS Microbiol Ecol       Date:  2019-12-01       Impact factor: 4.194
  5 in total

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