| Literature DB >> 20044842 |
Abstract
I propose a technique for reading the base sequence of a single DNA molecule using a graphene nanogap to read the DNA's transverse conductance. Because graphene is a single atom thick, single-base resolution of the conductance is readily obtained. The nonlinear current-voltage characteristic is used to determine the base type independent of nanogap-width variations that cause the current to change by 5 orders of magnitude. The expected sequencing error rate is 0% up to a nanogap width of 1.6 nm.Entities:
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Year: 2010 PMID: 20044842 DOI: 10.1021/nl9029237
Source DB: PubMed Journal: Nano Lett ISSN: 1530-6984 Impact factor: 11.189