| Literature DB >> 20038088 |
Lisa M Manus1, Daniel J Mastarone, Emily A Waters, Xue-Qing Zhang, Elise A Schultz-Sikma, Keith W Macrenaris, Dean Ho, Thomas J Meade.
Abstract
A Gd(III)-nanodiamond conjugate [Gd(III)-ND] was prepared and characterized, enabling detection of nanodiamonds by MR imaging. The Gd(III)-ND particles significantly reduced the T(1) of water protons with a per-Gd(III) relaxivity of 58.82 +/- 1.18 mM(-1) s(-1) at 1.5 T (60 MHz). This represents a 10-fold increase compared to the monomer Gd(III) complex (r(1) = 5.42 +/- 0.20 mM(-1) s(-1)) and is among the highest per-Gd(III) relaxivities reported.Entities:
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Year: 2010 PMID： 20038088 PMCID： PMC2829273 DOI： 10.1021/nl903264h
Source DB: PubMed Journal: Nano Lett ISSN： 1530-6984 Impact factor: 11.189