| Literature DB >> 20020130 |
Michael Bergdorf1, Ivo F Sbalzarini, Petros Koumoutsakos.
Abstract
Reaction-diffusion processes on complex deforming surfaces are fundamental to a number of biological processes ranging from embryonic development to cancer tumor growth and angiogenesis. The simulation of these processes using continuum reaction-diffusion models requires computational methods capable of accurately tracking the geometric deformations and discretizing on them the governing equations. We employ a Lagrangian level-set formulation to capture the deformation of the geometry and use an embedding formulation and an adaptive particle method to discretize both the level-set equations and the corresponding reaction-diffusion. We validate the proposed method and discuss its advantages and drawbacks through simulations of reaction-diffusion equations on complex and deforming geometries.Entities:
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Year: 2009 PMID: 20020130 DOI: 10.1007/s00285-009-0315-2
Source DB: PubMed Journal: J Math Biol ISSN: 0303-6812 Impact factor: 2.259