| Literature DB >> 20007362 |
Ryan C Maves1, Roger M Castillo Oré, Kevin R Porter, Tadeusz J Kochel.
Abstract
We evaluated a novel psoralen-inactivated dengue virus type 1 (DENV-1) vaccine candidate in Mus musculus mice. Mice received intradermal alum or 5 to 10 ng of psoralen-inactivated virus. Anti-DENV-1 neutralizing antibody was detectable in 10/11 mice receiving a 10-ng dose at 90 days. Psoralen-inactivated DENV-1 is immunogenic in mice.Entities:
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Year: 2009 PMID: 20007362 PMCID: PMC2815535 DOI: 10.1128/CVI.00353-09
Source DB: PubMed Journal: Clin Vaccine Immunol ISSN: 1556-679X