PURPOSE: To evaluate the feasibility of spectral domain optical coherence tomography (SD-OCT) macular scanning as a means of studying the afferent visual system in nystagmus patients. METHODS: Nystagmus patients who underwent SD-OCT, clinical evaluation, and eye movement recordings were recruited for this prospective, single-center, noncomparative study. Three SD-OCT macular three-dimensional cube scans per eye (200 x 200 x 1024 samplings in a 6 x 6 mm region) were obtained for qualitative retinal morphology analysis. RESULTS: Nineteen patients (6-68 years; average, 19 years) were analyzed. Of these, 17 patients had infantile nystagmus syndrome, and 2 had fusion maldevelopment nystagmus; 17 patients (89%) had associated sensory system abnormalities, including 9 (47%) with albinism. Macular images were successfully obtained in all but 1 patient (95%). Of the 8 successfully imaged oculocutaneous patients, 7 patients demonstrated "fovea plana," and all demonstrated abnormal morphology. CONCLUSION: SD-OCT reliably provides detailed structural imaging of the fovea in nystagmus patients.
PURPOSE: To evaluate the feasibility of spectral domain optical coherence tomography (SD-OCT) macular scanning as a means of studying the afferent visual system in nystagmuspatients. METHODS:Nystagmuspatients who underwent SD-OCT, clinical evaluation, and eye movement recordings were recruited for this prospective, single-center, noncomparative study. Three SD-OCT macular three-dimensional cube scans per eye (200 x 200 x 1024 samplings in a 6 x 6 mm region) were obtained for qualitative retinal morphology analysis. RESULTS: Nineteen patients (6-68 years; average, 19 years) were analyzed. Of these, 17 patients had infantile nystagmus syndrome, and 2 had fusion maldevelopment nystagmus; 17 patients (89%) had associated sensory system abnormalities, including 9 (47%) with albinism. Macular images were successfully obtained in all but 1 patient (95%). Of the 8 successfully imaged oculocutaneous patients, 7 patients demonstrated "fovea plana," and all demonstrated abnormal morphology. CONCLUSION: SD-OCT reliably provides detailed structural imaging of the fovea in nystagmuspatients.
Authors: Maciej Wojtkowski; Tomasz Bajraszewski; Iwona Gorczyńska; Piotr Targowski; Andrzej Kowalczyk; Wojciech Wasilewski; Czesław Radzewicz Journal: Am J Ophthalmol Date: 2004-09 Impact factor: 5.258
Authors: Gabriel T Chong; Sina Farsiu; Sharon F Freedman; Neeru Sarin; Anjum F Koreishi; Joseph A Izatt; Cynthia A Toth Journal: Arch Ophthalmol Date: 2009-01
Authors: Je Hyun Seo; Young Suk Yu; Jeong Hun Kim; Ho Kyung Choung; Jang Won Heo; Seong-Joon Kim Journal: Ophthalmology Date: 2007-03-06 Impact factor: 12.079
Authors: Helena Lee; Jennifer Scott; Helen Griffiths; Jay E Self; Andrew Lotery Journal: Pigment Cell Melanoma Res Date: 2019-04-02 Impact factor: 4.693
Authors: H E Sepúlveda-Vázquez; C Villanueva-Mendoza; J C Zenteno; V Villegas-Ruiz; E Pelcastre-Luna; G García-Aguirre Journal: Int Ophthalmol Date: 2014-02-14 Impact factor: 2.031
Authors: Ruobing Qian; Oscar M Carrasco-Zevallos; Shwetha Mangalesh; Neeru Sarin; Lejla Vajzovic; Sina Farsiu; Joseph A Izatt; Cynthia A Toth Journal: Transl Vis Sci Technol Date: 2017-10-16 Impact factor: 3.283