PURPOSE: To document, in vivo, the foveal morphology and thickness in a patient with oculocutaneous albinism. METHODS: Observational case report. In a 10-year-old female with oculocutaneous albinism, multiple cross-sectional scans of the fovea were performed using optical coherence tomography. RESULTS: Optical coherence tomography scans were unable to detect the foveal pit. A widespread thickening of the retina occurred throughout the entire fovea with no difference from the surrounding macula. The foveal thickness was greater than 300 microm in the eyes of this patient with oculocutaneous albinism, compared with 150 microm in the normal eye. The inner retina had a highly reflective signal on optical coherence tomography. CONCLUSION: Optical coherence tomography demonstrated in the anatomical location of the fovea a highly reflective inner retinal signal, possibly consistent with multiple layers of ganglion cells, and it confirmed foveal hypoplasia in a patient with oculocutaneous albinism.
PURPOSE: To document, in vivo, the foveal morphology and thickness in a patient with oculocutaneous albinism. METHODS: Observational case report. In a 10-year-old female with oculocutaneous albinism, multiple cross-sectional scans of the fovea were performed using optical coherence tomography. RESULTS: Optical coherence tomography scans were unable to detect the foveal pit. A widespread thickening of the retina occurred throughout the entire fovea with no difference from the surrounding macula. The foveal thickness was greater than 300 microm in the eyes of this patient with oculocutaneous albinism, compared with 150 microm in the normal eye. The inner retina had a highly reflective signal on optical coherence tomography. CONCLUSION: Optical coherence tomography demonstrated in the anatomical location of the fovea a highly reflective inner retinal signal, possibly consistent with multiple layers of ganglion cells, and it confirmed foveal hypoplasia in a patient with oculocutaneous albinism.
Authors: Zhaohui Hu; Kai Wang; Morgan Bertsch; Taylor Dunn; Taylor Kehoe; Andrew D Kemerley; Megan Helms; Sajag Bhattarai; Wanda Pfeifer; Todd E Scheetz; Arlene V Drack Journal: Doc Ophthalmol Date: 2019-03-29 Impact factor: 2.379
Authors: Scott O'Brien; Jingyun Wang; Heather A Smith; Dana L Donaldson; Kathryn M Haider; Gavin J Roberts; Derek T Sprunger; Daniel E Neely; David A Plager Journal: Graefes Arch Clin Exp Ophthalmol Date: 2015-07-02 Impact factor: 3.117
Authors: Paul Hahn; Justin Migacz; Rachelle O'Connell; Ramiro S Maldonado; Joseph A Izatt; Cynthia A Toth Journal: Ophthalmic Surg Lasers Imaging Date: 2011-07
Authors: H E Sepúlveda-Vázquez; C Villanueva-Mendoza; J C Zenteno; V Villegas-Ruiz; E Pelcastre-Luna; G García-Aguirre Journal: Int Ophthalmol Date: 2014-02-14 Impact factor: 2.031
Authors: Ramiro S Maldonado; Joseph A Izatt; Neeru Sarin; David K Wallace; Sharon Freedman; C Michael Cotten; Cynthia A Toth Journal: Invest Ophthalmol Vis Sci Date: 2010-01-13 Impact factor: 4.799