Literature DB >> 19998024

Long-term results of vaginal repairs with and without xenograft reinforcement.

Lone Mouritsen1, Manuela Kronschnabl, Gunnar Lose.   

Abstract

INTRODUCTION AND HYPOTHESIS: The aim of this paper is to study if xenograft reinforcement of vaginal repair reduces recurrence of prolapse.
METHODS: Results 1-5 years after vaginal repair were studied in 41 cases with xenograft and in 82 matched controls without. Symptoms were evaluated by a validated questionnaire and anatomy by pelvic organ prolapse quantification (POPQ).
RESULTS: Significant more cases, 97% versus 81% controls, felt cured or much improved (p = 0.02); 11% of cases and 19% of controls had POP symptoms, POPQ > -1 was found in 31% cases and 24% controls. Defining recurrence as POPQ > -1 plus symptoms revealed recurrence in 3% of cases and 12% controls. None of the recurrence rates was significantly different for cases versus controls. No vaginal erosions were seen. Previous surgery was a significant risk factor with odds ratio 7.3 for another recurrence.
CONCLUSIONS: Recurrence rates defined by POPQ plus symptoms were low compared to literature. Xenograft reinforcement might improve results.

Mesh:

Year:  2009        PMID: 19998024     DOI: 10.1007/s00192-009-1061-0

Source DB:  PubMed          Journal:  Int Urogynecol J        ISSN: 0937-3462            Impact factor:   2.894


  28 in total

Review 1.  Symptoms and outcome measures of pelvic organ prolapse.

Authors:  Matthew D Barber
Journal:  Clin Obstet Gynecol       Date:  2005-09       Impact factor: 2.190

2.  Outcomes with porcine graft placement in the anterior vaginal compartment in patients who undergo high vaginal uterosacral suspension and cystocele repair.

Authors:  Thomas L Wheeler; Holly E Richter; Angela G Duke; Kathryn L Burgio; David T Redden; R Edward Varner
Journal:  Am J Obstet Gynecol       Date:  2006-05       Impact factor: 8.661

3.  Rectocele repair: a randomized trial of three surgical techniques including graft augmentation.

Authors:  Marie Fidela R Paraiso; Matthew D Barber; Tristi W Muir; Mark D Walters
Journal:  Am J Obstet Gynecol       Date:  2006-12       Impact factor: 8.661

Review 4.  The use of graft materials in vaginal pelvic floor surgery.

Authors:  M Huebner; Y Hsu; D E Fenner
Journal:  Int J Gynaecol Obstet       Date:  2006-01-19       Impact factor: 3.561

5.  Functional and anatomical outcome of anterior and posterior vaginal prolapse repair with prolene mesh.

Authors:  Rodolfo Milani; Stefano Salvatore; Marco Soligo; Paola Pifarotti; Michele Meschia; Marina Cortese
Journal:  BJOG       Date:  2005-01       Impact factor: 6.531

6.  Posterior vaginal wall prolapse does not correlate with fecal symptoms or objective measures of anorectal function.

Authors:  Giovanna Marques da Silva; Brooke Gurland; Ambereen Sleemi; Gil Levy
Journal:  Am J Obstet Gynecol       Date:  2006-12       Impact factor: 8.661

7.  Risk factors for the recurrence of pelvic organ prolapse after vaginal surgery: a review at 5 years after surgery.

Authors:  I Diez-Itza; I Aizpitarte; A Becerro
Journal:  Int Urogynecol J Pelvic Floor Dysfunct       Date:  2007-02-28

8.  Results of cystocele repair: a comparison of traditional anterior colporrhaphy, polypropylene mesh and porcine dermis.

Authors:  LiAnn N Handel; Tara L Frenkl; Young H Kim
Journal:  J Urol       Date:  2007-05-17       Impact factor: 7.450

9.  Prevalence of urinary and fecal incontinence and symptoms of genital prolapse in women.

Authors:  Uustal Fornell Eva; Wingren Gun; Kjølhede Preben
Journal:  Acta Obstet Gynecol Scand       Date:  2003-03       Impact factor: 3.636

10.  Long-term patient satisfaction with prolapse surgery in general gynecology.

Authors:  Emma Hawkins; Sundararajah Raajkumar; Mohammad Masood
Journal:  Int Urogynecol J Pelvic Floor Dysfunct       Date:  2008-05-29
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  5 in total

1.  Biologic grafts for cystocele repair: does concomitant midline fascial plication improve surgical outcomes?

Authors:  Deborah R Karp; Thais V Peterson; Ayman Mahdy; Gamal Ghoniem; Vivian C Aguilar; G Willy Davila
Journal:  Int Urogynecol J       Date:  2011-04-12       Impact factor: 2.894

Review 2.  Tissue engineering as a potential alternative or adjunct to surgical reconstruction in treating pelvic organ prolapse.

Authors:  M Boennelycke; S Gras; G Lose
Journal:  Int Urogynecol J       Date:  2012-09-01       Impact factor: 2.894

3.  Use of Surgisis mesh in the management of polypropylene mesh erosion into the vagina.

Authors:  Su-Yen Khong; Alan Lam
Journal:  Int Urogynecol J       Date:  2010-08-11       Impact factor: 2.894

4.  Stem cell augmented mesh materials: an in vitro and in vivo study.

Authors:  Federico Spelzini; Stefano Manodoro; Matteo Frigerio; Gabriella Nicolini; Daniele Maggioni; Elisabetta Donzelli; Lina Altomare; Silvia Farè; Fanny Veneziano; Federica Avezza; Giovanni Tredici; Rodolfo Milani
Journal:  Int Urogynecol J       Date:  2014-11-22       Impact factor: 2.894

5.  Use of surgisis for treatment of anterior and posterior vaginal prolapse.

Authors:  Sara Armitage; Elvis I Seman; Marc J N C Keirse
Journal:  Obstet Gynecol Int       Date:  2012-01-15
  5 in total

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