Literature DB >> 21484371

Biologic grafts for cystocele repair: does concomitant midline fascial plication improve surgical outcomes?

Deborah R Karp1, Thais V Peterson, Ayman Mahdy, Gamal Ghoniem, Vivian C Aguilar, G Willy Davila.   

Abstract

INTRODUCTION AND HYPOTHESIS: This study aims to compare the efficacy of porcine graft-augmented anterior prolapse repair with and without underlying pubocervical fascia plication.
METHODS: Women with symptomatic anterior prolapse who underwent transvaginal repair, using biologic graft via transobturator approach, were retrospectively studied. An initial cohort had the graft placed without fascial plication. A second cohort had graft placement as an overlay to fascial plication.
RESULTS: Between March 2005 and September 2008, 65 subjects underwent anterior repair with biologic graft; 35 without fascial plication and 30 as an overlay to plication. At 6 months follow-up, anatomic recurrence (Ba>/= -1) was significantly higher in the non-plicated group (18/35, 51%) compared with the plicated group (2/30, 7%) p < 0.01. Five (5/35, 14%) in the non-plicated group compared with none (0/30) in the plicated group underwent further treatment (p = 0.06).
CONCLUSIONS: When using a non-crosslinked biologic graft for repair of anterior vaginal prolapse, we recommend the addition of concomitant midline fascial plication to enhance anatomic outcome.

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Year:  2011        PMID: 21484371     DOI: 10.1007/s00192-011-1408-1

Source DB:  PubMed          Journal:  Int Urogynecol J        ISSN: 0937-3462            Impact factor:   2.894


  15 in total

1.  The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction.

Authors:  R C Bump; A Mattiasson; K Bø; L P Brubaker; J O DeLancey; P Klarskov; B L Shull; A R Smith
Journal:  Am J Obstet Gynecol       Date:  1996-07       Impact factor: 8.661

Review 2.  InteXen tissue processing and laboratory study.

Authors:  J Christian Winters
Journal:  Int Urogynecol J Pelvic Floor Dysfunct       Date:  2006-06

Review 3.  Xenograft use in reconstructive pelvic surgery: a review of the literature.

Authors:  Emanuel C Trabuco; Christopher J Klingele; John B Gebhart
Journal:  Int Urogynecol J Pelvic Floor Dysfunct       Date:  2007-01-17

4.  Contemporary approaches to cystocele repair: a survey of AUGS members.

Authors:  Stuart Shippey; Robert E Gutman; Lieschen H Quiroz; Victoria L Handa
Journal:  J Reprod Med       Date:  2008-11       Impact factor: 0.142

5.  The outcome of transobturator cystocele repair using biocompatible porcine dermis graft: our experience with 32 cases.

Authors:  Ayman Mahdy; Mostafa Elmissiry; Gamal Ghoniem
Journal:  Int Urogynecol J Pelvic Floor Dysfunct       Date:  2008-06-05

6.  Long-term results of vaginal repairs with and without xenograft reinforcement.

Authors:  Lone Mouritsen; Manuela Kronschnabl; Gunnar Lose
Journal:  Int Urogynecol J       Date:  2009-12-09       Impact factor: 2.894

7.  Clinical implications of the biology of grafts: conclusions of the 2005 IUGA Grafts Roundtable.

Authors:  G Willy Davila; Harold Drutz; Jan Deprest
Journal:  Int Urogynecol J Pelvic Floor Dysfunct       Date:  2006-06

8.  Results of cystocele repair: a comparison of traditional anterior colporrhaphy, polypropylene mesh and porcine dermis.

Authors:  LiAnn N Handel; Tara L Frenkl; Young H Kim
Journal:  J Urol       Date:  2007-05-17       Impact factor: 7.450

Review 9.  Graft use in transvaginal pelvic organ prolapse repair: a systematic review.

Authors:  Vivian W Sung; Rebecca G Rogers; Joseph I Schaffer; Ethan M Balk; Katrin Uhlig; Joseph Lau; Husam Abed; Thomas L Wheeler; Michelle Y Morrill; Jeffrey L Clemons; David D Rahn; James C Lukban; Lior Lowenstein; Kimberly Kenton; Stephen B Young
Journal:  Obstet Gynecol       Date:  2008-11       Impact factor: 7.661

10.  Anterior repair with or without collagen matrix reinforcement: a randomized controlled trial.

Authors:  Nathan L Guerette; Thais V Peterson; Oscar A Aguirre; Douglas M VanDrie; Daniel H Biller; G Willy Davila
Journal:  Obstet Gynecol       Date:  2009-07       Impact factor: 7.661

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  3 in total

1.  Selection of patients in whom vaginal graft use may be appropriate. Consensus of the 2nd IUGA Grafts Roundtable: optimizing safety and appropriateness of graft use in transvaginal pelvic reconstructive surgery.

Authors:  G Willy Davila; Kaven Baessler; Michel Cosson; Linda Cardozo
Journal:  Int Urogynecol J       Date:  2012-03-07       Impact factor: 2.894

2.  The Comparison of Outcomes of Transvaginal Mesh Surgery with and without Midline Fascial Plication for the Treatment of Anterior Vaginal Prolapse: A Randomized Controlled Trial.

Authors:  Ching-Hsiang Chiang; Chun-Shuo Hsu; Dah-Ching Ding
Journal:  J Clin Med       Date:  2021-04-27       Impact factor: 4.241

3.  Mesh complications in female pelvic floor reconstructive surgery and their management: A systematic review.

Authors:  Hemendra N Shah; Gopal H Badlani
Journal:  Indian J Urol       Date:  2012-04
  3 in total

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