Literature DB >> 1997388

Structural organization and polymorphism of the alpha satellite DNA sequences of chromosomes 13 and 21 as revealed by pulse field gel electrophoresis.

B Marçais1, M Bellis, A Gérard, M Pagès, Y Boublik, G Roizès.   

Abstract

More than 30 unrelated individuals were analysed by pulse field gel electrophoresis for the alphoid centromeric sequences of chromosomes 13 and 21. These individuals had DNA patterns all different from each other and were most probably heterozygous at both loci. When several nuclear families were analysed in this manner, segregation was shown to be Mendelian, and no recombination event was detected over the 150 meioses scored in this study. Alphoid DNA sequences, therefore, constitute highly polymorphic centromeric markers, which can be used in linkage analysis for loci close to the centromeres of chromosomes 13 and 21.

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Year:  1991        PMID： 1997388     DOI： 10.1007/bf00202418

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  23 in total

1.  Long-range organization of tandem arrays of alpha satellite DNA at the centromeres of human chromosomes: high-frequency array-length polymorphism and meiotic stability.

Authors:  R Wevrick; H F Willard
Journal:  Proc Natl Acad Sci U S A       Date:  1989-12       Impact factor: 11.205

2.  Predisposing locus for Alzheimer's disease on chromosome 21.

Authors:  A M Goate; A R Haynes; M J Owen; M Farrall; L A James; L Y Lai; M J Mullan; P Roques; M N Rossor; R Williamson
Journal:  Lancet       Date:  1989-02-18       Impact factor: 79.321

3.  Structure of the major block of alphoid satellite DNA on the human Y chromosome.

Authors:  C Tyler-Smith; W R Brown
Journal:  J Mol Biol       Date:  1987-06-05       Impact factor: 5.469

4.  The action of a restriction endonuclease on higher organism DNA.

Authors:  E M Southern; G Roizes
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1974

5.  Hypervariable 'minisatellite' regions in human DNA.

Authors:  A J Jeffreys; V Wilson; S L Thein
Journal:  Nature       Date:  1985 Mar 7-13       Impact factor: 49.962

6.  Homologous alpha satellite sequences on human acrocentric chromosomes with selectivity for chromosomes 13, 14 and 21: implications for recombination between nonhomologues and Robertsonian translocations.

Authors:  K H Choo; B Vissel; R Brown; R G Filby; E Earle
Journal:  Nucleic Acids Res       Date:  1988-02-25       Impact factor: 16.971

7.  Macromolecular organization of human centromeric regions reveals high-frequency, polymorphic macro DNA repeats.

Authors:  E W Jabs; C A Goble; G R Cutting
Journal:  Proc Natl Acad Sci U S A       Date:  1989-01       Impact factor: 11.205

8.  Chromosome-specific alpha satellite DNA from human chromosome 1: hierarchical structure and genomic organization of a polymorphic domain spanning several hundred kilobase pairs of centromeric DNA.

Authors:  J S Waye; S J Durfy; D Pinkel; S Kenwrick; M Patterson; K E Davies; H F Willard
Journal:  Genomics       Date:  1987-09       Impact factor: 5.736

9.  Gene for von Recklinghausen neurofibromatosis is in the pericentromeric region of chromosome 17.

Authors:  D Barker; E Wright; K Nguyen; L Cannon; P Fain; D Goldgar; D T Bishop; J Carey; B Baty; J Kivlin
Journal:  Science       Date:  1987-05-29       Impact factor: 47.728

10.  Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis.

Authors:  D C Schwartz; C R Cantor
Journal:  Cell       Date:  1984-05       Impact factor: 41.582
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  12 in total

1.  Hypothesis: for the worst and for the best, L1Hs retrotransposons actively participate in the evolution of the human centromeric alphoid sequences.

Authors:  A M Laurent; J Puechberty; G Roizès
Journal:  Chromosome Res       Date:  1999       Impact factor: 5.239

2.  TaqI reveals two independent alphoid polymorphisms on human chromosomes 13 and 21.

Authors:  B Marçais; A Gérard; M Bellis; G Roizès
Journal:  Hum Genet       Date:  1991-01       Impact factor: 4.132

3.  Consensus higher order repeats and frequency of string distributions in human genome.

Authors:  Vladimir Paar; Ivan Basar; Marija Rosandić; Matko Gluncić
Journal:  Curr Genomics       Date:  2007-04       Impact factor: 2.236

4.  SINE and LINE within human centromeres.

Authors:  C Prades; A M Laurent; J Puechberty; Y Yurov; G Roizés
Journal:  J Mol Evol       Date:  1996-01       Impact factor: 2.395

5.  Analysis of pericentromeric chromosome 21 specific YAC clones by FISH: identification of new markers for molecular-cytogenetic application.

Authors:  Y B Yurov; A M Laurent; B Marcais; S G Vorsanova; G Roizes
Journal:  Hum Genet       Date:  1995-03       Impact factor: 4.132

6.  A rapid and simple method to isolate and characterize highly polymorphic markers from the centromeric regions of the human chromosomes.

Authors:  A M Laurent; B Marçais; M Muleris; G Roizès
Journal:  Nucleic Acids Res       Date:  1994-01-25       Impact factor: 16.971

Review 7.  Alpha satellite DNA biology: finding function in the recesses of the genome.

Authors:  Shannon M McNulty; Beth A Sullivan
Journal:  Chromosome Res       Date:  2018-07-05       Impact factor: 5.239

8.  On the mode of evolution of alpha satellite DNA in human populations.

Authors:  B Marçais; J P Charlieu; B Allain; E Brun; M Bellis; G Roizès
Journal:  J Mol Evol       Date:  1991-07       Impact factor: 2.395

9.  Organization of the variant domains of alpha satellite DNA on human chromosome 21.

Authors:  B Marçais; A M Laurent; J P Charlieu; G Roizès
Journal:  J Mol Evol       Date:  1993-08       Impact factor: 2.395

10.  Mouse centromere mapping using oligonucleotide probes that detect variants of the minor satellite.

Authors:  D Kipling; H E Wilson; A R Mitchell; B A Taylor; H J Cooke
Journal:  Chromosoma       Date:  1994-03       Impact factor: 4.316
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