Literature DB >> 19949055

Effects of ceftobiprole and oxacillin on mecA expression in methicillin-resistant Staphylococcus aureus clinical isolates.

Wenchi Shang1, Todd A Davies, Robert K Flamm, Karen Bush.   

Abstract

Induction of mecA by ceftobiprole and oxacillin in 18 methicillin-resistant Staphylococcus aureus clinical isolates with various SCCmec cassettes was examined using reverse transcriptase PCR. The magnitude of mecA induction, 3- to 65-fold for ceftobiprole and 2- to 69-fold for oxacillin, did not correlate with ceftobiprole MICs (<or=4 microg/ml), although the 11 isolates with at least 13-fold induction by oxacillin all had oxacillin MICs of >or=256 microg/ml. No correlation between magnitude of induction and SCCmec type was found.

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Year:  2009        PMID： 19949055      PMCID： PMC2812168          DOI： 10.1128/AAC.01024-09

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  20 in total

1.  Correlation between regulation of mecA transcription and expression of methicillin resistance in staphylococci.

Authors:  C Ryffel; F H Kayser; B Berger-Bächi
Journal:  Antimicrob Agents Chemother       Date:  1992-01       Impact factor: 5.191

2.  Novel multiplex PCR assay for characterization and concomitant subtyping of staphylococcal cassette chromosome mec types I to V in methicillin-resistant Staphylococcus aureus.

Authors:  Kunyan Zhang; Jo-Ann McClure; Sameer Elsayed; Thomas Louie; John M Conly
Journal:  J Clin Microbiol       Date:  2005-10       Impact factor: 5.948

3.  Update to the multiplex PCR strategy for assignment of mec element types in Staphylococcus aureus.

Authors:  Catarina Milheiriço; Duarte C Oliveira; Hermínia de Lencastre
Journal:  Antimicrob Agents Chemother       Date:  2007-06-18       Impact factor: 5.191

4.  Antistaphylococcal activity of ceftobiprole, a new broad-spectrum cephalosporin.

Authors:  Tatiana Bogdanovich; Lois M Ednie; Stuart Shapiro; Peter C Appelbaum
Journal:  Antimicrob Agents Chemother       Date:  2005-10       Impact factor: 5.191

5.  Combination of multiplex PCRs for staphylococcal cassette chromosome mec type assignment: rapid identification system for mec, ccr, and major differences in junkyard regions.

Authors:  Yoko Kondo; Teruyo Ito; Xiao Xue Ma; Shinya Watanabe; Barry N Kreiswirth; Jerome Etienne; Keiichi Hiramatsu
Journal:  Antimicrob Agents Chemother       Date:  2006-10-16       Impact factor: 5.191

6.  Assignment of Staphylococcus isolates to groups by spa typing, SmaI macrorestriction analysis, and multilocus sequence typing.

Authors:  B Strommenger; C Kettlitz; T Weniger; D Harmsen; A W Friedrich; W Witte
Journal:  J Clin Microbiol       Date:  2006-07       Impact factor: 5.948

Review 7.  Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing.

Authors:  F C Tenover; R D Arbeit; R V Goering; P A Mickelsen; B E Murray; D H Persing; B Swaminathan
Journal:  J Clin Microbiol       Date:  1995-09       Impact factor: 5.948

Review 8.  Methicillin resistance in staphylococci: molecular and biochemical basis and clinical implications.

Authors:  H F Chambers
Journal:  Clin Microbiol Rev       Date:  1997-10       Impact factor: 26.132

9.  Binding of ceftobiprole and comparators to the penicillin-binding proteins of Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae.

Authors:  Todd A Davies; Malcolm G P Page; Wenchi Shang; Ted Andrew; Malgosia Kania; Karen Bush
Journal:  Antimicrob Agents Chemother       Date:  2007-04-30       Impact factor: 5.191

10.  blaI and blaR1 regulate beta-lactamase and PBP 2a production in methicillin-resistant Staphylococcus aureus.

Authors:  C J Hackbarth; H F Chambers
Journal:  Antimicrob Agents Chemother       Date:  1993-05       Impact factor: 5.191
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  3 in total

1.  VraR Binding to the Promoter Region of agr Inhibits Its Function in Vancomycin-Intermediate Staphylococcus aureus (VISA) and Heterogeneous VISA.

Authors:  Yuanyuan Dai; Wenjiao Chang; Changcheng Zhao; Jing Peng; Liangfei Xu; Huaiwei Lu; Shusheng Zhou; Xiaoling Ma
Journal:  Antimicrob Agents Chemother       Date:  2017-04-24       Impact factor: 5.191

2.  Small colony variants have a major role in stability and persistence of Staphylococcus aureus biofilms.

Authors:  Zulfiqar Ali Mirani; Mubashir Aziz; Seema Ismat Khan
Journal:  J Antibiot (Tokyo)       Date:  2014-08-27       Impact factor: 2.649

3.  Methicillin-Resistant Staphylococcus aureus Grown on Vancomycin-Supplemented Screening Agar Displays Enhanced Biofilm Formation.

Authors:  Wenjiao Chang; Ding Ding; Shanshan Zhang; Yuanyuan Dai; Qing Pan; Huaiwei Lu; Qingli Luo; Jilong Shen; Xiaoling Ma
Journal:  Antimicrob Agents Chemother       Date:  2015-10-12       Impact factor: 5.191
  3 in total

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