Literature DB >> 19948566

Prospective multicentre systematic guideline-based management of patients referred to the Syncope Units of general hospitals.

Michele Brignole1, Andrea Ungar, Ivo Casagranda, Michele Gulizia, Maurizio Lunati, Fabrizio Ammirati, Attilio Del Rosso, Massimo Sasdelli, Massimo Santini, Roberto Maggi, Elena Vitale, Alessandro Morrione, Giuseppina Maura Francese, Maria Rita Vecchi, Franco Giada.   

Abstract

AIMS: Although an organizational model for syncope management facilities was proposed in the 2004 guidelines of the European Society of Cardiology (ESC), its implementation in clinical practice and its effectiveness are largely unknown. METHODS AND
RESULTS: This prospective study enrolled 941 consecutive patients referred to the Syncope Units of nine general hospitals from 15 March 2008 to 15 September 2008. A median of 15 patients per month were examined in each unit, but the five older units had a two-fold higher volume of activity than the four newer ones (instituted <1 year before): 23 vs. 12, P = 0.02. These figures give an estimated volume of 163 and 60 patients per 100,000 inhabitants per year, respectively. Referrals: 60% from out-of-hospital services, 11% immediate and 13% delayed referrals from the Emergency Department, and 16% hospitalized patients. A diagnosis was established on initial evaluation in 191 (21%) patients and early by means of 2.9 +/- 1.6 tests in 541 (61%) patients. A likely reflex cause was established in 67%, orthostatic hypotension in 4%, cardiac in 6% and non-syncopal in 5% of the cases. The cause of syncope remained unexplained in 159 (18%) patients, despite a mean of 3.5 +/- 1.8 tests per patient. These latter patients were older, more frequently had structural heart disease or electrocardiographic abnormalities, unpredictable onset of syncope due to the lack of prodromes, and higher OESIL and EGSIS risk scores than the other groups of patients. The mean costs of diagnostic evaluation was 209 euro per outpatient and 1073 euro per inpatient. The median cost of hospital stay was 2990 euro per patient.
CONCLUSION: We documented the current practice of syncope management in specialized facilities that have adopted the management model proposed by the ESC. The results are useful for those who wish to replicate this model in other hospitals. Syncope remains unexplained during in-hospital evaluation in more complex cases at higher risk.

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Year:  2010        PMID: 19948566     DOI: 10.1093/europace/eup370

Source DB:  PubMed          Journal:  Europace        ISSN: 1099-5129            Impact factor:   5.214


  13 in total

1.  Application Of The American College Of Emergency Physicians (ACEP) Recommendations And a Risk Stratification Score (OESIL) For Patients With Syncope Admitted From The Emergency Department.

Authors:  Adrian Baranchuk; William McIntyre; William Harper; Carlos A Morillo
Journal:  Indian Pacing Electrophysiol J       Date:  2011-10-02

2.  Arrhythmias are not to blame for all cardiac syncope patients: left atrial myxoma causing syncope in a middle-aged man.

Authors:  Ali Raza Rajani; Reem Naif Muaz; Pushpa Rani Govindaswamy; Muhammad Hamid Mian
Journal:  BMJ Case Rep       Date:  2015-04-15

3.  The semiology of tilt-induced psychogenic pseudosyncope.

Authors:  Martijn R Tannemaat; Julius van Niekerk; Robert H Reijntjes; Roland D Thijs; Richard Sutton; J Gert van Dijk
Journal:  Neurology       Date:  2013-07-19       Impact factor: 9.910

4.  Classification of orthostatic intolerance through data analytics.

Authors:  Steven Gilmore; Joseph Hart; Justen Geddes; Christian H Olsen; Jesper Mehlsen; Pierre Gremaud; Mette S Olufsen
Journal:  Med Biol Eng Comput       Date:  2021-02-13       Impact factor: 2.602

Review 5.  Vasovagal syncope with asystole: the role of cardiac pacing.

Authors:  Michele Brignole; Marco Tomaino; Alessio Gargaro
Journal:  Clin Auton Res       Date:  2017-07-01       Impact factor: 4.435

Review 6.  Key challenges in the current management of syncope.

Authors:  Richard Sutton; Michele Brignole; David G Benditt
Journal:  Nat Rev Cardiol       Date:  2012-07-17       Impact factor: 32.419

7.  The prevalence and prognostic significance of near syncope and syncope: a prospective study of 395 cases in an emergency department (the SPEED study).

Authors:  Yvonne Greve; Felicitas Geier; Steffen Popp; Thomas Bertsch; Katrin Singler; Florian Meier; Alexander Smolarsky; Harald Mang; Christian Müller; Michael Christ
Journal:  Dtsch Arztebl Int       Date:  2014-03-21       Impact factor: 5.594

Review 8.  [Do we need syncope units? : Experience from Bolzano, South Tyrol (Italy)].

Authors:  Matthias Unterhuber; Marco Tomaino; Michele Brignole
Journal:  Herzschrittmacherther Elektrophysiol       Date:  2018-05-14

9.  Discrepancy between clinical practice and standardized indications for an implantable loop recorder in patients with unexplained syncope.

Authors:  Elena Vitale; Andrea Ungar; Roberto Maggi; Maura Francese; Maurizio Lunati; Roberto Colaceci; Attilio Del Rosso; Antonio Castro; Massimo Santini; Silvia Giuli; Lara Belgini; Ivo Casagranda; Michele Brignole
Journal:  Europace       Date:  2010-10       Impact factor: 5.214

10.  Costs of unstructured investigation of unexplained syncope: insights from a micro-costing analysis of the observational PICTURE registry.

Authors:  Nils Edvardsson; Claudia Wolff; Stelios Tsintzos; Guido Rieger; Nicholas J Linker
Journal:  Europace       Date:  2015-03-10       Impact factor: 5.214

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