Literature DB >> 19946764

A study comparing endoscopic ultrasound (EUS) and computed tomography (CT) in staging oesophageal cancer and their role in clinical decision making.

Duminda Subasinghe1, Dharmabandhu Nandadeva Samarasekera.   

Abstract

BACKGROUND AND AIM: Computed tomography (CT) and endoscopic ultrasound (EUS) are part of the regular preoperative staging protocol in oesophageal cancer. At present, EUS is increasingly being used for preoperative locoregional staging of oesophageal cancer. The aim of this study is to compare EUS and CT findings and their role in clinical decision making.
METHODS: The CT staging of 30 patients with oesophageal carcinoma was compared with EUS. This is a single centre-based study, and the EUS was carried out by a single operator.
RESULTS: The mean age was 58.2 years. On EUS, one (3.3%), five (16.7%), 16(53.3%) and eight (26.7%) patients had T1, T2, T3 and T4 tumours, respectively, compared with CT which showed 12(40%), nine (30%) and seven (23.3%) patients with T2, T3 and T4 tumours. On CT, two (6.7%) were shown as no tumour (T0). EUS revealed lymph node involvement in 25 (83.3%) patients compared with CT which indicated lymph node involvement in seven (23.3%) patients. On EUS, coeliac node involvement was shown in four (13.3%) patients (M1). The TNM staging of CT and EUS were comparable in nine (30%) patients. EUS staging revealed a more advanced stage of oesophageal cancer in 17 (56.7%) patients. Preoperative EUS staging changed the decision of management in 15 (50%) patients (P < 0.005).
CONCLUSIONS: EUS staging revealed a more advanced stage of cancer in the majority of patients. It appears to be far more superior in detecting lymph node involvement compared with CT. Therefore, EUS may have a significant impact on deciding the treatment modality of a patient with oesophageal carcinoma.

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Year:  2010        PMID: 19946764     DOI: 10.1007/s12029-009-9105-8

Source DB:  PubMed          Journal:  J Gastrointest Cancer


  24 in total

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