Literature DB >> 19946172

A long DNA segment in a linear nanoscale Paul trap.

Sony Joseph1, Weihua Guan, Mark A Reed, Predrag S Krstic.   

Abstract

We study the dynamics of a linearly distributed line charge such as single stranded DNA (ssDNA) in a nanoscale, linear 2D Paul trap in vacuum. Using molecular dynamics simulations we show that a line charge can be trapped effectively in the trap for a well defined range of stability parameters. We investigated (i) a flexible bonded string of charged beads and (ii) a ssDNA polymer of variable length, for various trap parameters. A line charge undergoes oscillations or rotations as it moves, depending on its initial angle, the position of the center of mass and the velocity. The stability region for a strongly bonded line of charged beads is similar to that of a single ion with the same charge to mass ratio. Single stranded DNA as long as 40 nm does not fold or curl in the Paul trap, but could undergo rotations about the center of mass. However, we show that a stretching field in the axial direction can effectively prevent the rotations and increase the confinement stability.

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Year:  2009        PMID: 19946172      PMCID: PMC3269948          DOI: 10.1088/0957-4484/21/1/015103

Source DB:  PubMed          Journal:  Nanotechnology        ISSN: 0957-4484            Impact factor:   3.874


  29 in total

1.  Sequence-specific detection of individual DNA strands using engineered nanopores.

Authors:  S Howorka; S Cheley; H Bayley
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2.  A point-charge force field for molecular mechanics simulations of proteins based on condensed-phase quantum mechanical calculations.

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Journal:  J Comput Chem       Date:  2003-12       Impact factor: 3.376

3.  Exploring the helix-coil transition via all-atom equilibrium ensemble simulations.

Authors:  Eric J Sorin; Vijay S Pande
Journal:  Biophys J       Date:  2005-01-21       Impact factor: 4.033

4.  First-principles transversal DNA conductance deconstructed.

Authors:  X-G Zhang; Predrag S Krstić; Radomir Zikić; Jack C Wells; Miguel Fuentes-Cabrera
Journal:  Biophys J       Date:  2006-05-05       Impact factor: 4.033

Review 5.  Toward nanoscale genome sequencing.

Authors:  Declan Ryan; Maryam Rahimi; John Lund; Ranjana Mehta; Babak A Parviz
Journal:  Trends Biotechnol       Date:  2007-07-19       Impact factor: 19.536

Review 6.  Nanopore-based single-molecule DNA analysis.

Authors:  Ken Healy
Journal:  Nanomedicine (Lond)       Date:  2007-08       Impact factor: 5.307

7.  Single-strand DNA molecule translocation through nanoelectrode gaps.

Authors:  Xiongce Zhao; Christina M Payne; Peter T Cummings; James W Lee
Journal:  Nanotechnology       Date:  2007-09-19       Impact factor: 3.874

8.  A molecular dynamics simulation study on trapping ions in a nanoscale Paul trap.

Authors:  Xiongce Zhao; Predrag S Krstic
Journal:  Nanotechnology       Date:  2008-04-08       Impact factor: 3.874

9.  Characterization of individual polynucleotide molecules using a membrane channel.

Authors:  J J Kasianowicz; E Brandin; D Branton; D W Deamer
Journal:  Proc Natl Acad Sci U S A       Date:  1996-11-26       Impact factor: 11.205

Review 10.  The potential and challenges of nanopore sequencing.

Authors:  Daniel Branton; David W Deamer; Andre Marziali; Hagan Bayley; Steven A Benner; Thomas Butler; Massimiliano Di Ventra; Slaven Garaj; Andrew Hibbs; Xiaohua Huang; Stevan B Jovanovich; Predrag S Krstic; Stuart Lindsay; Xinsheng Sean Ling; Carlos H Mastrangelo; Amit Meller; John S Oliver; Yuriy V Pershin; J Michael Ramsey; Robert Riehn; Gautam V Soni; Vincent Tabard-Cossa; Meni Wanunu; Matthew Wiggin; Jeffery A Schloss
Journal:  Nat Biotechnol       Date:  2008-10       Impact factor: 54.908

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  5 in total

1.  Paul trapping of charged particles in aqueous solution.

Authors:  Weihua Guan; Sony Joseph; Jae Hyun Park; Predrag S Krstic; Mark A Reed
Journal:  Proc Natl Acad Sci U S A       Date:  2011-05-23       Impact factor: 11.205

2.  Stability of an aqueous quadrupole micro-trap.

Authors:  Jae Hyun Park; Predrag S Krstić
Journal:  J Phys Condens Matter       Date:  2012-03-30       Impact factor: 2.333

3.  Control and reversal of the electrophoretic force on DNA in a charged nanopore.

Authors:  Binquan Luan; Aleksei Aksimentiev
Journal:  J Phys Condens Matter       Date:  2010-10-29       Impact factor: 2.333

4.  Control Of Screening Of A Charged Particle In Electrolytic Aqueous Paul Trap.

Authors:  Jae Hyun Park; Predrag S Krsti
Journal:  AIP Conf Proc       Date:  2011

5.  Thermal noise in aqueous quadrupole micro- and nano-traps.

Authors:  Jae Hyun Park; Predrag S Krstić
Journal:  Nanoscale Res Lett       Date:  2012-02-27       Impact factor: 4.703

  5 in total

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