Literature DB >> 19944149

Difficulties in recruiting older people in clinical trials: an examination of barriers and solutions.

I Ridda1, C R MacIntyre, R I Lindley, T C Tan.   

Abstract

Limited information exists regarding optimal methods for the recruitment and retention of older people in clinical trials. The aim of this review is to identify common barriers to the recruitment of older people in clinical trials and to propose solutions to overcome these barriers. A review of literature was performed to identify common difficulties in recruiting older people. This in combination with our experience during recruitment for a randomized control trial, have highlighted numerous barriers. Population-specific recruitment strategies, simple informed-consent processes, and effective communication between the researcher and subject are effective strategies to overcome these barriers.

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Year:  2009        PMID: 19944149     DOI: 10.1016/j.vaccine.2009.10.081

Source DB:  PubMed          Journal:  Vaccine        ISSN: 0264-410X            Impact factor:   3.641


  40 in total

1.  A model for the design and implementation of a participant recruitment registry for clinical studies of older adults.

Authors:  N Maritza Dowling; Nevin Olson; Thomas Mish; Preethy Kaprakattu; Carey Gleason
Journal:  Clin Trials       Date:  2012-01-24       Impact factor: 2.486

2.  Keys to success with clinical trials.

Authors:  Seymour Katz; Heather Dufficy; Christy John
Journal:  Gastroenterol Hepatol (N Y)       Date:  2011-02

3.  Recruitment Challenges for Low-Risk Health System Intervention Trials in Older Adults: A Case Study.

Authors:  Kathryn Anzuoni; Terry S Field; Kathleen M Mazor; Yanhua Zhou; Lawrence D Garber; Alok Kapoor; Jerry H Gurwitz
Journal:  J Am Geriatr Soc       Date:  2020-07-25       Impact factor: 5.562

Review 4.  Frailty and exercise interventions : Evidence and barriers for exercise programs.

Authors:  E Freiberger; W Kemmler; M Siegrist; C Sieber
Journal:  Z Gerontol Geriatr       Date:  2016-09-21       Impact factor: 1.281

5.  Establishing the Feasibility of a Tablet-Based Consent Process with Older Adults: A Mixed-Methods Study.

Authors:  Nimali Jayasinghe; B Isabel Moallem; Margo Kakoullis; Mary-Jane Ojie; Lili Sar-Graycar; Katarzyna Wyka; M Cary Reid; John P Leonard
Journal:  Gerontologist       Date:  2019-01-09

6.  Characteristics of participants consenting versus declining follow-up for up to 10 years in a randomized clinical trial.

Authors:  Alice J Sheffet; Jenifer H Voeks; Ariane Mackey; William Brooks; Wayne M Clark; Michael D Hill; Virginia J Howard; Susan E Hughes; MeeLee Tom; Mary E Longbottom; Thomas G Brott
Journal:  Clin Trials       Date:  2015-06-29       Impact factor: 2.486

7.  Discussions of cancer clinical trials with the National Cancer Institute's Cancer Information Service.

Authors:  Margaret M Byrne; Julie Kornfeld; Robin Vanderpool; Marc Belanger
Journal:  J Health Commun       Date:  2011-12-12

8.  Measurement of Function Post Hip Fracture: Testing a Comprehensive Measurement Model of Physical Function.

Authors:  Barbara Resnick; Ann L Gruber-Baldini; Gregory Hicks; Glen Ostir; N Jennifer Klinedinst; Denise Orwig; Jay Magaziner
Journal:  Rehabil Nurs       Date:  2015-10-23       Impact factor: 1.625

9.  Lifestyle interventions and independence for elders study: recruitment and baseline characteristics.

Authors:  Anthony P Marsh; Laura C Lovato; Nancy W Glynn; Kimberly Kennedy; Cynthia Castro; Kathryn Domanchuk; Erica McDavitt; Ruben Rodate; Michael Marsiske; Joanne McGloin; Erik J Groessl; Marco Pahor; Jack M Guralnik
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2013-05-28       Impact factor: 6.053

10.  The Randomized Control Trial of the Effects of Testosterone and a Nutritional Supplement On Hospital Admissions in Undernourished, Community Dwelling, Older People.

Authors:  R Visvanathan; C Piantadosi; K Lange; V Naganathan; P Hunter; I D Cameron; I Chapman
Journal:  J Nutr Health Aging       Date:  2016       Impact factor: 4.075

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