BACKGROUND: Intracoronary optical coherence tomography (OCT) is a high-resolution imaging modality used for evaluation of coronary lesion morphology. However, current time-domain OCT (TD-OCT) have a number of limitations with regard to both procedural usage and safety in the clinical setting. The next-generation frequency-domain OCT (FD-OCT), which has a much faster frame rate and pullback speed than TD-OCT, is expected to overcome these limitations. The aim of this study was to evaluate the feasibility and usability of next generation FD-OCT in the assessment of coronary lesions. METHODS: A comparison study was performed between FD-OCT and TD-OCT from the aspect of usability (set-up time), qualitatively (rate of clear image segment), and safety (adverse event) in 14 ischemic heart disease patients with 20 previously implanted coronary stents. RESULTS: The mean time of the OCT procedure in this study from setup to completion of image acquisition was 3.2 +/- 0.8 min for FD-OCT and 11.2 +/- 2.5 min for TD-OCT (P < 0.01). In qualitative image assessment, FD-OCT has the potential to yield a higher rate of clear image segments (CIS) than TD-OCT (99.4% vs. 80.8%, respectively; P < 0.01). In addition to these improved characteristics, there were no ischemic ECG changes or arrhythmia associated with FD-OCT. CONCLUSIONS: The next-generation intracoronary FD-OCT has better performance in the clinical setting and the potential to overcome several limitations of conventional TD-OCT systems.
BACKGROUND: Intracoronary optical coherence tomography (OCT) is a high-resolution imaging modality used for evaluation of coronary lesion morphology. However, current time-domain OCT (TD-OCT) have a number of limitations with regard to both procedural usage and safety in the clinical setting. The next-generation frequency-domain OCT (FD-OCT), which has a much faster frame rate and pullback speed than TD-OCT, is expected to overcome these limitations. The aim of this study was to evaluate the feasibility and usability of next generation FD-OCT in the assessment of coronary lesions. METHODS: A comparison study was performed between FD-OCT and TD-OCT from the aspect of usability (set-up time), qualitatively (rate of clear image segment), and safety (adverse event) in 14 ischemic heart diseasepatients with 20 previously implanted coronary stents. RESULTS: The mean time of the OCT procedure in this study from setup to completion of image acquisition was 3.2 +/- 0.8 min for FD-OCT and 11.2 +/- 2.5 min for TD-OCT (P < 0.01). In qualitative image assessment, FD-OCT has the potential to yield a higher rate of clear image segments (CIS) than TD-OCT (99.4% vs. 80.8%, respectively; P < 0.01). In addition to these improved characteristics, there were no ischemic ECG changes or arrhythmia associated with FD-OCT. CONCLUSIONS: The next-generation intracoronary FD-OCT has better performance in the clinical setting and the potential to overcome several limitations of conventional TD-OCT systems.
Authors: C A Given; G F Attizzani; M R Jones; C N Ramsey; W H Brooks; M A Costa; H G Bezerra Journal: AJNR Am J Neuroradiol Date: 2013-02-07 Impact factor: 3.825
Authors: Rodolfo Staico; Marco A Costa; Daniel Chamié; Hiram Bezerra; Luciana V Armaganijan; Ricardo A Costa; José Ribamar Costa; Dimytri Siqueira; Marinella Centemero; Áurea Chaves; Luiz Fernando Tanajura; Alexandre Abizaid; Fausto Feres; J Eduardo M R Sousa; Amanda G M R Sousa Journal: Int J Cardiovasc Imaging Date: 2013-03-03 Impact factor: 2.357