Literature DB >> 19932098

Experimental and computational determination of tRNA dynamics.

Rebecca W Alexander1, John Eargle, Zaida Luthey-Schulten.   

Abstract

As the molecular representation of the genetic code, tRNA plays a central role in the translational machinery where it interacts with several proteins and other RNAs during the course of protein synthesis. These interactions exploit the dynamic flexibility of tRNA. In this minireview, we discuss the effects of modified bases, ions, and proteins on tRNA structure and dynamics and the challenges of observing its motions over the cycle of translation.

Mesh：

Substances：

Year:  2010        PMID： 19932098     DOI： 10.1016/j.febslet.2009.11.061

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  27 in total

1.  Excited states of ribosome translocation revealed through integrative molecular modeling.

Authors:  Paul C Whitford; Aqeel Ahmed; Yanan Yu; Scott P Hennelly; Florence Tama; Christian M T Spahn; José N Onuchic; Karissa Y Sanbonmatsu
Journal:  Proc Natl Acad Sci U S A       Date:  2011-11-11       Impact factor: 11.205

2.  Double-stranded RNA under force and torque: similarities to and striking differences from double-stranded DNA.

Authors:  Jan Lipfert; Gary M Skinner; Johannes M Keegstra; Toivo Hensgens; Tessa Jager; David Dulin; Mariana Köber; Zhongbo Yu; Serge P Donkers; Fang-Chieh Chou; Rhiju Das; Nynke H Dekker
Journal:  Proc Natl Acad Sci U S A       Date:  2014-10-13       Impact factor: 11.205

3.  Simulating movement of tRNA through the ribosome during hybrid-state formation.

Authors:  Paul C Whitford; Karissa Y Sanbonmatsu
Journal:  J Chem Phys       Date:  2013-09-28       Impact factor: 3.488

4.  NetworkView: 3D display and analysis of protein·RNA interaction networks.

Authors:  John Eargle; Zaida Luthey-Schulten
Journal:  Bioinformatics       Date:  2012-09-14       Impact factor: 6.937

5.  Dynamical network of residue-residue contacts reveals coupled allosteric effects in recognition, catalysis, and mutation.

Authors:  Urmi Doshi; Michael J Holliday; Elan Z Eisenmesser; Donald Hamelberg
Journal:  Proc Natl Acad Sci U S A       Date:  2016-04-11       Impact factor: 11.205

Review 6.  Hierarchy of RNA functional dynamics.

Authors:  Anthony M Mustoe; Charles L Brooks; Hashim M Al-Hashimi
Journal:  Annu Rev Biochem       Date:  2014-03-05       Impact factor: 23.643

7.  Explaining the striking difference in twist-stretch coupling between DNA and RNA: A comparative molecular dynamics analysis.

Authors:  Korbinian Liebl; Tomas Drsata; Filip Lankas; Jan Lipfert; Martin Zacharias
Journal:  Nucleic Acids Res       Date:  2015-10-12       Impact factor: 16.971

8.  Rational design of an orthogonal tryptophanyl nonsense suppressor tRNA.

Authors:  Randall A Hughes; Andrew D Ellington
Journal:  Nucleic Acids Res       Date:  2010-06-22       Impact factor: 16.971

9.  Mapping Mechanical Force Propagation through Biomolecular Complexes.

Authors:  Constantin Schoeler; Rafael C Bernardi; Klara H Malinowska; Ellis Durner; Wolfgang Ott; Edward A Bayer; Klaus Schulten; Michael A Nash; Hermann E Gaub
Journal:  Nano Lett       Date:  2015-08-19       Impact factor: 11.189

10.  Topological constraints are major determinants of tRNA tertiary structure and dynamics and provide basis for tertiary folding cooperativity.

Authors:  Anthony M Mustoe; Charles L Brooks; Hashim M Al-Hashimi
Journal:  Nucleic Acids Res       Date:  2014-09-12       Impact factor: 16.971
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.