PURPOSE: To investigate ethnic differences in optic nerve head topography. METHODS: This is a cross-sectional university-based comparative study of 180 normal subjects (43 African-American, 45 Asian, 48 Hispanic, and 44 white subjects) ages 19-40 years. Optic nerve head parameters including optic disc size, cup-disc ratio, rim area, rim volume, cup volume, and maximal cup depth were measured using a confocal scanning laser ophthalmoscope (Heidelberg Retina Tomograph). Differences among groups were evaluated using analysis of variance. RESULTS: Disc area, cup volume, maximal cup depth, and vertical cup-disc ratio were largest in African-Americans, intermediate in Asians and Hispanics, and smallest in whites; for these parameters the differences between African-Americans and whites were statistically significant. Significant differences were also found between African-Americans and Hispanics for cup volume, and between African-Americans and Asians for vertical cup-disc ratio and maximal cup depth. Rim volume and rim area were not significantly different among the four ethnic groups. CONCLUSIONS: Ethnic differences in the normal optic nerve are present and should be taken into a ccount when evaluating the optic disc for glaucoma and other optic neuropathies.
PURPOSE: To investigate ethnic differences in optic nerve head topography. METHODS: This is a cross-sectional university-based comparative study of 180 normal subjects (43 African-American, 45 Asian, 48 Hispanic, and 44 white subjects) ages 19-40 years. Optic nerve head parameters including optic disc size, cup-disc ratio, rim area, rim volume, cup volume, and maximal cup depth were measured using a confocal scanning laser ophthalmoscope (Heidelberg Retina Tomograph). Differences among groups were evaluated using analysis of variance. RESULTS: Disc area, cup volume, maximal cup depth, and vertical cup-disc ratio were largest in African-Americans, intermediate in Asians and Hispanics, and smallest in whites; for these parameters the differences between African-Americans and whites were statistically significant. Significant differences were also found between African-Americans and Hispanics for cup volume, and between African-Americans and Asians for vertical cup-disc ratio and maximal cup depth. Rim volume and rim area were not significantly different among the four ethnic groups. CONCLUSIONS: Ethnic differences in the normal optic nerve are present and should be taken into a ccount when evaluating the optic disc for glaucoma and other optic neuropathies.
Authors: Christopher A Girkin; Pamela A Sample; Jeffrey M Liebmann; Sonia Jain; Christopher Bowd; Lida M Becerra; Felipe A Medeiros; Lyne Racette; Keri A Dirkes; Robert N Weinreb; Linda M Zangwill Journal: Arch Ophthalmol Date: 2010-05
Authors: A Harris; Y Ishii; H S Chung; C P Jonescu-Cuypers; L J McCranor; L Kagemann; H J Garzozi Journal: Br J Ophthalmol Date: 2003-02 Impact factor: 4.638
Authors: Lindsay A Rhodes; Carrie Huisingh; John Johnstone; Massimo Fazio; Brandon Smith; Mark Clark; J Crawford Downs; Cynthia Owsley; Michael J A Girard; Jean Martial Mari; Christopher Girkin Journal: Invest Ophthalmol Vis Sci Date: 2014-11-20 Impact factor: 4.799