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Literature DB >> 19907483

Drug discovery: Predicting promiscuity.

Andrew L Hopkins.

Abstract

Mesh：

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Year: 2009 PMID： 19907483 DOI： 10.1038/462167a

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

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5 in total

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2. Ligand-target prediction using Winnow and naive Bayesian algorithms and the implications of overall performance statistics.

Authors: Florian Nigsch; Andreas Bender; Jeremy L Jenkins; John B O Mitchell
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3. Drug-target network.

Authors: Muhammed A Yildirim; Kwang-Il Goh; Michael E Cusick; Albert-László Barabási; Marc Vidal
Journal: Nat Biotechnol Date: 2007-10 Impact factor: 54.908

4. Predicting new molecular targets for known drugs.

Authors: Michael J Keiser; Vincent Setola; John J Irwin; Christian Laggner; Atheir I Abbas; Sandra J Hufeisen; Niels H Jensen; Michael B Kuijer; Roberto C Matos; Thuy B Tran; Ryan Whaley; Richard A Glennon; Jérôme Hert; Kelan L H Thomas; Douglas D Edwards; Brian K Shoichet; Bryan L Roth
Journal: Nature Date: 2009-11-01 Impact factor: 49.962

5. Relating protein pharmacology by ligand chemistry.

Authors: Michael J Keiser; Bryan L Roth; Blaine N Armbruster; Paul Ernsberger; John J Irwin; Brian K Shoichet
Journal: Nat Biotechnol Date: 2007-02 Impact factor: 54.908

5 in total

44 in total

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Journal: Curr Protoc Nucleic Acid Chem Date: 2011-06

2. What happens if you pose the wrong questions?

Authors: James A Timmons
Journal: J Physiol Date: 2011-10-01 Impact factor: 5.182

Review 3. Systems Pharmacology Links GPCRs with Retinal Degenerative Disorders.

Authors: Yu Chen; Krzysztof Palczewski
Journal: Annu Rev Pharmacol Toxicol Date: 2015-03-23 Impact factor: 13.820

4. Revealing the macromolecular targets of complex natural products.

Authors: Daniel Reker; Anna M Perna; Tiago Rodrigues; Petra Schneider; Michael Reutlinger; Bettina Mönch; Andreas Koeberle; Christina Lamers; Matthias Gabler; Heinrich Steinmetz; Rolf Müller; Manfred Schubert-Zsilavecz; Oliver Werz; Gisbert Schneider
Journal: Nat Chem Date: 2014-11-02 Impact factor: 24.427

5. PreDTIs: prediction of drug-target interactions based on multiple feature information using gradient boosting framework with data balancing and feature selection techniques.

Authors: S M Hasan Mahmud; Wenyu Chen; Yongsheng Liu; Md Abdul Awal; Kawsar Ahmed; Md Habibur Rahman; Mohammad Ali Moni
Journal: Brief Bioinform Date: 2021-03-12 Impact factor: 11.622

Review 6. Physiologically-based pharmacokinetic models: approaches for enabling personalized medicine.

Authors: Clara Hartmanshenn; Megerle Scherholz; Ioannis P Androulakis
Journal: J Pharmacokinet Pharmacodyn Date: 2016-09-19 Impact factor: 2.745

7. Ethionamide Pharmacokinetics/Pharmacodynamics-derived Dose, the Role of MICs in Clinical Outcome, and the Resistance Arrow of Time in Multidrug-resistant Tuberculosis.

Authors: Devyani Deshpande; Jotam G Pasipanodya; Stellah G Mpagama; Shashikant Srivastava; Paula Bendet; Thearith Koeuth; Pooi S Lee; Scott K Heysell; Tawanda Gumbo
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