Literature DB >> 15060530

Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia.

Bryan L Roth1, Douglas J Sheffler, Wesley K Kroeze.   

Abstract

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Year:  2004        PMID： 15060530     DOI： 10.1038/nrd1346

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


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  306 in total

Review 1.  Ingestion-controlling network: what's language got to do with it?

Authors:  Michael Myslobodsky; Richard Coppola
Journal:  Rev Neurosci       Date:  2010       Impact factor: 4.353

2.  Discovery of β-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy.

Authors:  John A Allen; Julianne M Yost; Vincent Setola; Xin Chen; Maria F Sassano; Meng Chen; Sean Peterson; Prem N Yadav; Xi-ping Huang; Bo Feng; Niels H Jensen; Xin Che; Xu Bai; Stephen V Frye; William C Wetsel; Marc G Caron; Jonathan A Javitch; Bryan L Roth; Jian Jin
Journal:  Proc Natl Acad Sci U S A       Date:  2011-10-24       Impact factor: 11.205

3.  Dual targeting of histone deacetylase and topoisomerase II with novel bifunctional inhibitors.

Authors:  William Guerrant; Vishal Patil; Joshua C Canzoneri; Adegboyega K Oyelere
Journal:  J Med Chem       Date:  2012-02-13       Impact factor: 7.446

Review 4.  Diagnosing the decline in pharmaceutical R&D efficiency.

Authors:  Jack W Scannell; Alex Blanckley; Helen Boldon; Brian Warrington
Journal:  Nat Rev Drug Discov       Date:  2012-03-01       Impact factor: 84.694

Review 5.  Is rational antipsychotic polytherapy feasible? A selective review.

Authors:  Rune Andreas Kroken; Erik Johnsen
Journal:  Curr Psychiatry Rep       Date:  2012-06       Impact factor: 5.285

6.  Simplified proteomics approach to discover protein-ligand interactions.

Authors:  Youngil Chang; Jonathan P Schlebach; Ross A VerHeul; Chiwook Park
Journal:  Protein Sci       Date:  2012-07-23       Impact factor: 6.725

7.  Quantifying and predicting the promiscuity and isoform specificity of small-molecule cytochrome P450 inhibitors.

Authors:  Abhinav Nath; Michael A Zientek; Benjamin J Burke; Ying Jiang; William M Atkins
Journal:  Drug Metab Dispos       Date:  2010-09-14       Impact factor: 3.922

8.  Identification of diaryl 5-amino-1,2,4-oxadiazoles as tubulin inhibitors: the special case of 3-(2-fluorophenyl)-5-(4-methoxyphenyl)amino-1,2,4-oxadiazole.

Authors:  Andrei A Gakh; Andrey V Sosnov; Mikhail Krasavin; Tam Luong Nguyen; Ernest Hamel
Journal:  Bioorg Med Chem Lett       Date:  2013-01-11       Impact factor: 2.823

Review 9.  Chemokine receptor antagonists: overcoming developmental hurdles.

Authors:  Richard Horuk
Journal:  Nat Rev Drug Discov       Date:  2008-12-12       Impact factor: 84.694

10.  5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology.

Authors:  Yao Peng; John D McCorvy; Kasper Harpsøe; Katherine Lansu; Shuguang Yuan; Petr Popov; Lu Qu; Mengchen Pu; Tao Che; Louise F Nikolajsen; Xi-Ping Huang; Yiran Wu; Ling Shen; Walden E Bjørn-Yoshimoto; Kang Ding; Daniel Wacker; Gye Won Han; Jianjun Cheng; Vsevolod Katritch; Anders A Jensen; Michael A Hanson; Suwen Zhao; David E Gloriam; Bryan L Roth; Raymond C Stevens; Zhi-Jie Liu
Journal:  Cell       Date:  2018-02-01       Impact factor: 41.582
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