OBJECTIVE: To evaluate anatomic and sexual outcomes in women with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome after laparoscopic Davydov (laparoscopic peritoneal vaginoplasty). DESIGN: Prospective follow-up study of patients with MRKH syndrome after vaginoplasty (Design classification: II-2). SETTING: Academic hospital. PATIENTS: Patients with MRKH syndrome and frequency-matched age-comparable healthy controls. INTERVENTION: Thirty-one patients with MRKH syndrome underwent surgery with the procedure, and their clinical, surgical, and follow-up data were recorded. A Female Sexual Function Index (FSFI) questionnaire was administrated to evaluate sexual functions of patients who became sexually active and compared them with 50 randomly selected, age-matched healthy women. MEASUREMENTS: FSFI scores in women with MRKH syndrome and in control subjects. Clinical and anatomic measurements of neovagina. MAIN RESULTS: The laparoscopic Davydov was successfully completed in all 31 cases, with 24 patients monitored. The mean length of the neovagina was 6.27+/-1.25 cm. There was no statistical difference in the total FSFI score between the case and control groups. There is indication that shorter neovaginal length, especially of<7 cm, appears to be associated with lower total FSFI scores. CONCLUSION: Laparoscopic Davydov is a safe, effective treatment of Mayer-Rokitansky-Kuster-Hauser syndrome with minimal invasion and a relatively low complication rate.
OBJECTIVE: To evaluate anatomic and sexual outcomes in women with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome after laparoscopic Davydov (laparoscopic peritoneal vaginoplasty). DESIGN: Prospective follow-up study of patients with MRKH syndrome after vaginoplasty (Design classification: II-2). SETTING: Academic hospital. PATIENTS: Patients with MRKH syndrome and frequency-matched age-comparable healthy controls. INTERVENTION: Thirty-one patients with MRKH syndrome underwent surgery with the procedure, and their clinical, surgical, and follow-up data were recorded. A Female Sexual Function Index (FSFI) questionnaire was administrated to evaluate sexual functions of patients who became sexually active and compared them with 50 randomly selected, age-matched healthy women. MEASUREMENTS: FSFI scores in women with MRKH syndrome and in control subjects. Clinical and anatomic measurements of neovagina. MAIN RESULTS: The laparoscopic Davydov was successfully completed in all 31 cases, with 24 patients monitored. The mean length of the neovagina was 6.27+/-1.25 cm. There was no statistical difference in the total FSFI score between the case and control groups. There is indication that shorter neovaginal length, especially of<7 cm, appears to be associated with lower total FSFI scores. CONCLUSION: Laparoscopic Davydov is a safe, effective treatment of Mayer-Rokitansky-Kuster-Hauser syndrome with minimal invasion and a relatively low complication rate.
Authors: Katharina Leithner; Andrea Naderer; Dorothee Hartung; Clara Abrahamowicz; Johanna Alexopoulos; Katharina Walch; René Wenzl; Eva Hilger Journal: PLoS One Date: 2015-04-22 Impact factor: 3.240