| Literature DB >> 19896376 |
Wanguo Wei1, Cuifang Cai, Smitha Kota, Virginia Takahashi, Feng Ni, A Donny Strosberg, John K Snyder.
Abstract
New small molecule inhibitors of HCV were discovered by screening a small library of indoline alkaloid-type compounds. An automated assay format was employed which allowed identification of dimerization inhibitors of core, the capsid protein of the virus. These compounds were subsequently shown to block production of infectious virus in hepatoma cells.Entities:
Mesh：
Substances：
Year: 2009 PMID： 19896376 PMCID： PMC2783740 DOI： 10.1016/j.bmcl.2009.10.070
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823