| Literature DB >> 19875137 |
Shugeng Cao1, Peggy J Brodie, Martin Callmander, Richard Randrianaivo, Etienne Rakotobe, Vincent E Rasamison, David G I Kingston.
Abstract
A study of an EtOH extract obtained from the roots of the Madagascan plant Terminalia tropophylla H. Perrier (Combretaceae) led to isolation of the oleanane-type triterpenoid saponin 1, the lignan derivative 2, and the two known saponins arjunglucoside I (3) and sericoside (4). The structures of compounds 1 (terminaliaside A) and 2 (4'-O-cinnamoyl cleomiscosin A) were elucidated using 1D and 2D NMR experiments and mass spectrometry. Compound 1 showed antiproliferative activity against the A2780 human ovarian cancer cell line with an IC(50) value of 1.2 microM. 2009 Elsevier Ltd. All rights reserved.Entities:
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Year: 2009 PMID: 19875137 PMCID: PMC2813959 DOI: 10.1016/j.phytochem.2009.09.027
Source DB: PubMed Journal: Phytochemistry ISSN: 0031-9422 Impact factor: 4.072