Literature DB >> 19870943

A SOLUBLE ANTIGEN OF LYMPHOCYTIC CHORIOMENINGITIS : II. CHARACTERISTICS OF THE ANTIGEN AND ITS USE IN PRECIPITIN REACTIONS.

J E Smadel1, M J Wall, R D Baird.   

Abstract

The soluble antigen of lymphocytic choriomeningitis which is readily separable from the virus is a relatively stable substance and appears to be of a protein nature. A specific precipitin reaction can be demonstrated when immune serum is added to solutions of antigen which have been freed of certain serologically inactive substances. The complement-fixation and precipitation reactions which occur in the presence of immune serum and non-infectious extracts of splenic tissue obtained from guinea pigs moribund with lymphocytic choriomeningitis seem to be manifestations of union of the same soluble antigen and its antibody. On the other hand, the antisoluble substance antibodies and neutralizing substances appear to be different entities.

Entities:  

Year:  1940        PMID： 19870943      PMCID： PMC2135000          DOI： 10.1084/jem.71.1.43

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  5 in total

1.  A SOLUBLE ANTIGEN OF LYMPHOCYTIC CHORIOMENINGITIS : I. SEPARATION OF SOLUBLE ANTIGEN FROM VIRUS.

Authors:  J E Smadel; R D Baird; M J Wall
Journal:  J Exp Med       Date:  1939-06-30       Impact factor: 14.307

2.  IMMUNOLOGICAL AND CHEMICAL INVESTIGATIONS OF VACCINE VIRUS : VI. ISOLATION OF A HEAT-STABLE, SEROLOGICALLY ACTIVE SUBSTANCE FROM TISSUES INFECTED WITH VACCINE VIRUS.

Authors:  R F Parker; T M Rivers
Journal:  J Exp Med       Date:  1937-01-31       Impact factor: 14.307

3.  A HIGH SPEED VACUUM CENTRIFUGE SUITABLE FOR THE STUDY OF FILTERABLE VIRUSES.

Authors:  J H Bauer; E G Pickels
Journal:  J Exp Med       Date:  1936-09-30       Impact factor: 14.307

4.  INFECTIOUS MYXOMATOSIS OF RABBITS : STUDIES OF A SOLUBLE ANTIGEN ASSOCIATED WITH THE DISEASE.

Authors:  T M Rivers; S M Ward; J E Smadel
Journal:  J Exp Med       Date:  1939-01-01       Impact factor: 14.307

5.  IMMUNOLOGICAL AND CHEMICAL INVESTIGATIONS OF VACCINE VIRUS : III. RESPONSE OF RABBITS TO INACTIVE ELEMENTARY BODIES OF VACCINIA AND TO VIRUS-FREE EXTRACTS OF VACCINE VIRUS.

Authors:  R F Parker; T M Rivers
Journal:  J Exp Med       Date:  1936-01-01       Impact factor: 14.307
  5 in total
  6 in total

1.  SOLUBLE ANTIGEN OF BOVINE VIRAL DIARRHEA VIRUS. I. INTRACELLULAR SYNTHESIS, SEPARATION AND CHARACTERIZATION.

Authors:  D E GUTEKUNST; W A MALMQUIST
Journal:  Arch Gesamte Virusforsch       Date:  1965

2.  Characterization of bovine viral diarrhea viruses. V. Morphology of characteristic particles studied by electron microscopy.

Authors:  A E Ritchie; A L Fernelius
Journal:  Arch Gesamte Virusforsch       Date:  1969

3.  Lymphocytic choriomeningitis virus. II. Characterization of extractable complement-fixing activity.

Authors:  H H Geschwender; G Rutter; F Lehmann-Grube
Journal:  Med Microbiol Immunol       Date:  1976-06-01       Impact factor: 3.402

4.  COMPLEMENT FIXATION WITH THE NEUROTROPIC VIRUSES.

Authors:  W P Havens; D W Watson; R H Green; G I Lavin; J E Smadel
Journal:  J Exp Med       Date:  1943-02-01       Impact factor: 14.307

5.  ELECTROPHORESIS OF THE COMPLEMENT-FIXING ANTIGEN OF HUMAN INFLUENZA VIRUS.

Authors:  J Bourdillon; E H Lennette
Journal:  J Exp Med       Date:  1940-06-30       Impact factor: 14.307

6.  A SOLUBLE ANTIGEN OF LYMPHOCYTIC CHORIOMENINGITIS : II. INDEPENDENCE OF ANTI-SOLUBLE SUBSTANCE ANTIBODIES AND NEUTRALIZING ANTIBODIES, AND THE ROLE OF SOLUBLE ANTIGEN AND INACTIVE VIRUS IN IMMUNITY TO INFECTION.

Authors:  J E Smadel; M J Wall
Journal:  J Exp Med       Date:  1940-09-30       Impact factor: 14.307
  6 in total

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