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Literature DB >> 19870598

IMMUNOLOGICAL AND CHEMICAL INVESTIGATIONS OF VACCINE VIRUS : VI. ISOLATION OF A HEAT-STABLE, SEROLOGICALLY ACTIVE SUBSTANCE FROM TISSUES INFECTED WITH VACCINE VIRUS.

Abstract

A method has been described by which a stable, serologically active substance has been isolated in a relatively pure state from tissues infected with vaccine virus. It has the characteristics of an alcohol-soluble protein which is not precipitated by boiling in a neutral aqueous solution. In a dilution of 1:640,000 it gives a precipitate when mixed with a serum containing antibodies against Craigie's S antigen of vaccine virus, but no visible reaction occurs when it is mixed with serum depleted of S antibodies by means of absorption.

Entities: Chemical

Year: 1937 PMID： 19870598 PMCID： PMC2133489 DOI： 10.1084/jem.65.2.243

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

5 in total

1. THE PURIFICATION OF THE ANTIBODIES IN TYPE I ANTI-PNEUMOCOCCUS SERUM, AND THE CHEMICAL NATURE OF THE TYPE-SPECIFIC PRECIPITIN REACTION.

Authors: B F Chow; W F Goebel
Journal: J Exp Med Date: 1935-07-31 Impact factor: 14.307

2. STUDIES ON THE SOLUBLE PRECIPITABLE SUBSTANCES OF VACCINIA : II. THE SOLUBLE PRECIPITABLE SUBSTANCES OF DERMAL VACCINE.

Authors: J Craigie; F O Wishart
Journal: J Exp Med Date: 1936-10-31 Impact factor: 14.307

3. IMMUNOLOGICAL AND CHEMICAL INVESTIGATIONS OF VACCINE VIRUS : I. PREPARATION OF ELEMENTARY BODIES OF VACCINIA.

Authors: R F Parker; T M Rivers
Journal: J Exp Med Date: 1935-06-30 Impact factor: 14.307

4. IMMUNOLOGICAL AND CHEMICAL INVESTIGATIONS OF VACCINE VIRUS : III. RESPONSE OF RABBITS TO INACTIVE ELEMENTARY BODIES OF VACCINIA AND TO VIRUS-FREE EXTRACTS OF VACCINE VIRUS.

Authors: R F Parker; T M Rivers
Journal: J Exp Med Date: 1936-01-01 Impact factor: 14.307

5. THE ANTIGENIC COMPLEX OF STREPTOCOCCUS HAEMOLYTICUS : II. CHEMICAL AND IMMUNOLOGICAL PROPERTIES OF THE PROTEIN FRACTIONS.

Authors: R C Lancefield
Journal: J Exp Med Date: 1928-02-29 Impact factor: 14.307

5 in total

11 in total

1. IMMUNOLOGICAL STUDIES OF A HEAT-STABLE SUBSTANCE ISOLATED FROM TISSUES INFECTED WITH VACCINE VIRUS.

Authors: R F Parker
Journal: J Exp Med Date: 1938-02-28 Impact factor: 14.307

2. A SOLUBLE ANTIGEN OF LYMPHOCYTIC CHORIOMENINGITIS : II. CHARACTERISTICS OF THE ANTIGEN AND ITS USE IN PRECIPITIN REACTIONS.

Authors: J E Smadel; M J Wall; R D Baird
Journal: J Exp Med Date: 1940-01-01 Impact factor: 14.307

10. THE OCCURRENCE DURING ACUTE INFECTIONS OF A PROTEIN NOT NORMALLY PRESENT IN THE BLOOD : III. IMMUNOLOGICAL PROPERTIES OF THE C-REACTIVE PROTEIN AND ITS DIFFERENTIATION FROM NORMAL BLOOD PROTEINS.

Authors: C M Macleod; O T Avery
Journal: J Exp Med Date: 1941-01-31 Impact factor: 14.307

IMMUNOLOGICAL AND CHEMICAL INVESTIGATIONS OF VACCINE VIRUS : VI. ISOLATION OF A HEAT-STABLE, SEROLOGICALLY ACTIVE SUBSTANCE FROM TISSUES INFECTED WITH VACCINE VIRUS.

1. THE PURIFICATION OF THE ANTIBODIES IN TYPE I ANTI-PNEUMOCOCCUS SERUM, AND THE CHEMICAL NATURE OF THE TYPE-SPECIFIC PRECIPITIN REACTION.

2. STUDIES ON THE SOLUBLE PRECIPITABLE SUBSTANCES OF VACCINIA : II. THE SOLUBLE PRECIPITABLE SUBSTANCES OF DERMAL VACCINE.

3. IMMUNOLOGICAL AND CHEMICAL INVESTIGATIONS OF VACCINE VIRUS : I. PREPARATION OF ELEMENTARY BODIES OF VACCINIA.

4. IMMUNOLOGICAL AND CHEMICAL INVESTIGATIONS OF VACCINE VIRUS : III. RESPONSE OF RABBITS TO INACTIVE ELEMENTARY BODIES OF VACCINIA AND TO VIRUS-FREE EXTRACTS OF VACCINE VIRUS.

5. THE ANTIGENIC COMPLEX OF STREPTOCOCCUS HAEMOLYTICUS : II. CHEMICAL AND IMMUNOLOGICAL PROPERTIES OF THE PROTEIN FRACTIONS.

1. IMMUNOLOGICAL STUDIES OF A HEAT-STABLE SUBSTANCE ISOLATED FROM TISSUES INFECTED WITH VACCINE VIRUS.

2. A SOLUBLE ANTIGEN OF LYMPHOCYTIC CHORIOMENINGITIS : II. CHARACTERISTICS OF THE ANTIGEN AND ITS USE IN PRECIPITIN REACTIONS.

3. SOME CONSTITUENTS OF ELEMENTARY BODIES OF VACCINIA.

4. THE LS-ANTIGEN OF VACCINIA : IV. CHEMICAL ANALYSIS OF LS AND THE EFFECT OF CHYMOTRYPSIN ON LS.

5. ELECTROPHORETIC STUDIES ON ELEMENTARY BODIES OF VACCINIA.

6. THE LS-ANTIGEN OF VACCINIA : II. ISOLATION OF A SINGLE SUBSTANCE CONTAINING BOTH L- AND S-ACTIVITY.

7. INFECTIOUS MYXOMATOSIS OF RABBITS : STUDIES OF A SOLUBLE ANTIGEN ASSOCIATED WITH THE DISEASE.

8. ELECTROPHORESIS OF THE COMPLEMENT-FIXING ANTIGEN OF HUMAN INFLUENZA VIRUS.

9. THE SOLUBLE MALARIAL ANTIGEN IN THE SERUM OF MONKEYS INFECTED WITH PLASMODIUM KNOWLESI.

10. THE OCCURRENCE DURING ACUTE INFECTIONS OF A PROTEIN NOT NORMALLY PRESENT IN THE BLOOD : III. IMMUNOLOGICAL PROPERTIES OF THE C-REACTIVE PROTEIN AND ITS DIFFERENTIATION FROM NORMAL BLOOD PROTEINS.