| Literature DB >> 1986248 |
B W Howell1, D E Afar, J Lew, E M Douville, P L Icely, D A Gray, J C Bell.
Abstract
We have cloned a novel kinase (STY) from an embryonal carcinoma cell line. Sequence analysis of the STY cDNA reveals that it shares sequence homology with serine/threonine-type kinases and yet the bacterial expression product of the STY cDNA appears to have serine-, threonine-, and tyrosine-phosphorylating activities. The predicted STY protein is highly basic and contains a putative nuclear localization signal. During differentiation, two new mRNAs were detected in addition to the embryonic transcript.Entities:
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Year: 1991 PMID: 1986248 PMCID: PMC359671 DOI: 10.1128/mcb.11.1.568-572.1991
Source DB: PubMed Journal: Mol Cell Biol ISSN: 0270-7306 Impact factor: 4.272