| Literature DB >> 2971141 |
N Sagata1, M Oskarsson, T Copeland, J Brumbaugh, G F Vande Woude.
Abstract
The c-mos proto-oncogene is expressed as a maternal mRNA in oocytes and early embryos of Xenopus laevis, but its translation product pp39mos is detectable only during progesterone-induced oocyte maturation. Microinjection of mos-specific antisense oligonucleotides into oocytes not only prevents expression of pp39mos, but also blocks germinal vesicle breakdown, indicating that it functions during reinitiation of meiotic division.Entities:
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Year: 1988 PMID: 2971141 DOI: 10.1038/335519a0
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962