Literature DB >> 19844597

Structure determination and absolute configuration of cannabichromanone derivatives from high potency Cannabis sativa.

Safwat A Ahmed1, Samir A Ross, Desmond Slade, Mohamed M Radwan, Ikhlas A Khan, Mahmoud A Elsohly.   

Abstract

Three new cannabichromanone derivatives were isolated from high potency cannabis, along with the known cannabichromanone. Full spectroscopic data, including the use of electronic circular dichroism and Mosher ester analysis to determine the absolute configuration of these compounds, are reported. All isolates were tested for antimicrobial, antimalarial, antileishmanial and anti-oxidant activity.

Entities:  

Year:  2008        PMID： 19844597      PMCID： PMC2763336          DOI： 10.1016/j.tetlet.2008.07.178

Source DB:  PubMed          Journal:  Tetrahedron Lett        ISSN： 0040-4039            Impact factor:   2.415


  20 in total

1.  Down-regulation of tissue inhibitor of metalloproteinases-1 in gliomas: a new marker of cannabinoid antitumoral activity?

Authors:  Cristina Blázquez; Arkaitz Carracedo; María Salazar; Mar Lorente; Ainara Egia; Luis González-Feria; Amador Haro; Guillermo Velasco; Manuel Guzmán
Journal:  Neuropharmacology       Date:  2007-07-01       Impact factor: 5.250

Review 2.  Circular dichroism, a powerful tool for the assessment of absolute configuration of flavonoids.

Authors:  Desmond Slade; Daneel Ferreira; Jannie P J Marais
Journal:  Phytochemistry       Date:  2005-09       Impact factor: 4.072

3.  Synergistic affective analgesic interaction between delta-9-tetrahydrocannabinol and morphine.

Authors:  John D Roberts; Chris Gennings; Margaret Shih
Journal:  Eur J Pharmacol       Date:  2005-12-22       Impact factor: 4.432

4.  Chromone derivatives from the filamentous fungus Lachnum sp. BCC 2424.

Authors:  Vatcharin Rukachaisirikul; Sirinya Chantaruk; Wipapan Pongcharoen; Masahiko Isaka; Sanisa Lapanun
Journal:  J Nat Prod       Date:  2006-06       Impact factor: 4.050

Review 5.  Serotonin, the prefrontal cortex, and the antidepressant-like effect of cannabinoids.

Authors:  Fabrício A Moreira
Journal:  J Neurosci       Date:  2007-12-05       Impact factor: 6.167

Review 6.  Chemical constituents of marijuana: the complex mixture of natural cannabinoids.

Authors:  Mahmoud A Elsohly; Desmond Slade
Journal:  Life Sci       Date:  2005-09-30       Impact factor: 5.037

7.  Anorexia of aging in long term care: is dronabinol an effective appetite stimulant?--a pilot study.

Authors:  M M G Wilson; C Philpot; J E Morley
Journal:  J Nutr Health Aging       Date:  2007 Mar-Apr       Impact factor: 4.075

Review 8.  Neuroprotective antioxidants from marijuana.

Authors:  A J Hampson; M Grimaldi; M Lolic; D Wink; R Rosenthal; J Axelrod
Journal:  Ann N Y Acad Sci       Date:  2000       Impact factor: 5.691

9.  Antiprotozoal and antimicrobial activities of O-alkylated and formylated acylphloroglucinols.

Authors:  Sandip B Bharate; Shabana I Khan; Nafees A M Yunus; Siddheshwar K Chauthe; Melissa R Jacob; Babu L Tekwani; Ikhlas A Khan; Inder Pal Singh
Journal:  Bioorg Med Chem       Date:  2006-10-10       Impact factor: 3.641

10.  Cannabinoid ester constituents from high-potency Cannabis sativa.

Authors:  Safwat A Ahmed; Samir A Ross; Desmond Slade; Mohamed M Radwan; Fazila Zulfiqar; Rae R Matsumoto; Yan-Tong Xu; Eddy Viard; Robert C Speth; Vardan T Karamyan; M A ElSohly
Journal:  J Nat Prod       Date:  2008-02-28       Impact factor: 4.050
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  10 in total

1.  Antidepressant-like effect of delta9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L.

Authors:  Abir T El-Alfy; Kelly Ivey; Keisha Robinson; Safwat Ahmed; Mohamed Radwan; Desmond Slade; Ikhlas Khan; Mahmoud ElSohly; Samir Ross
Journal:  Pharmacol Biochem Behav       Date:  2010-03-21       Impact factor: 3.533

2.  Isolation and Pharmacological Evaluation of Minor Cannabinoids from High-Potency Cannabis sativa.

Authors:  Mohamed M Radwan; Mahmoud A ElSohly; Abir T El-Alfy; Safwat A Ahmed; Desmond Slade; Afeef S Husni; Susan P Manly; Lisa Wilson; Suzanne Seale; Stephen J Cutler; Samir A Ross
Journal:  J Nat Prod       Date:  2015-05-22       Impact factor: 4.050

3.  Microbial metabolism of cannflavin A and B isolated from Cannabis sativa.

Authors:  Amany K Ibrahim; Mohamed M Radwan; Safwat A Ahmed; Desmond Slade; Samir A Ross; Mahmoud A ElSohly; Ikhlas A Khan
Journal:  Phytochemistry       Date:  2010-03-10       Impact factor: 4.072

4.  Minor oxygenated cannabinoids from high potency Cannabis sativa L.

Authors:  Safwat A Ahmed; Samir A Ross; Desmond Slade; Mohamed M Radwan; Ikhlas A Khan; Mahmoud A ElSohly
Journal:  Phytochemistry       Date:  2015-06-17       Impact factor: 4.072

5.  Highly stereoselective and scalable anti-aldol reactions using N-(p-dodecylphenylsulfonyl)-2-pyrrolidinecarboxamide: scope and origins of stereoselectivities.

Authors:  Hua Yang; Subham Mahapatra; Paul Ha-Yeon Cheong; Rich G Carter
Journal:  J Org Chem       Date:  2010-11-05       Impact factor: 4.354

6.  Biologically active cannabinoids from high-potency Cannabis sativa.

Authors:  Mohamed M Radwan; Mahmoud A Elsohly; Desmond Slade; Safwat A Ahmed; Ikhlas A Khan; Samir A Ross
Journal:  J Nat Prod       Date:  2009-05-22       Impact factor: 4.050

Review 7.  Designing microorganisms for heterologous biosynthesis of cannabinoids.

Authors:  Ângela Carvalho; Esben Halkjær Hansen; Oliver Kayser; Simon Carlsen; Felix Stehle
Journal:  FEMS Yeast Res       Date:  2017-06-01       Impact factor: 2.796

Review 8.  Structure-Activity Relationship of Cannabis Derived Compounds for the Treatment of Neuronal Activity-Related Diseases.

Authors:  Cristina Prandi; Marco Blangetti; Dvora Namdar; Hinanit Koltai
Journal:  Molecules       Date:  2018-06-25       Impact factor: 4.411

Review 9.  Cannabis sativa: Interdisciplinary Strategies and Avenues for Medical and Commercial Progression Outside of CBD and THC.

Authors:  Jackson M J Oultram; Joseph L Pegler; Timothy A Bowser; Luke J Ney; Andrew L Eamens; Christopher P L Grof
Journal:  Biomedicines       Date:  2021-02-26

Review 10.  Cannabinoids, Phenolics, Terpenes and Alkaloids of Cannabis.

Authors:  Mohamed M Radwan; Suman Chandra; Shahbaz Gul; Mahmoud A ElSohly
Journal:  Molecules       Date:  2021-05-08       Impact factor: 4.411
  10 in total

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