Literature DB >> 19833762

HARPing on about the DNA damage response during replication.

Robert Driscoll1, Karlene A Cimprich.   

Abstract

In this issue of Genes & Development, four papers report that the annealing helicase HepA-related protein (HARP, also known as SMARCAL1 [SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily a-like 1]) binds directly to the ssDNA-binding protein Replication protein A (RPA) and is recruited to sites of replicative stress. Knockdown of HARP results in hypersensitivity to multiple DNA-damaging agents and defects in fork stability or restart. These exciting insights reveal a key new player in the S-phase DNA damage response.

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Year:  2009        PMID： 19833762      PMCID： PMC2764495          DOI： 10.1101/gad.1860609

Source DB:  PubMed          Journal:  Genes Dev        ISSN： 0890-9369            Impact factor:   11.361


  63 in total

1.  Rtt109 acetylates histone H3 lysine 56 and functions in DNA replication.

Authors:  Junhong Han; Hui Zhou; Bruce Horazdovsky; Kangling Zhang; Rui-Ming Xu; Zhiguo Zhang
Journal:  Science       Date:  2007-02-02       Impact factor: 47.728

2.  Single- and double-stranded DNA: building a trigger of ATR-mediated DNA damage response.

Authors:  Lee Zou
Journal:  Genes Dev       Date:  2007-04-15       Impact factor: 11.361

Review 3.  Maintenance of fork integrity at damaged DNA and natural pause sites.

Authors:  Hélène Tourrière; Philippe Pasero
Journal:  DNA Repair (Amst)       Date:  2007-03-26

Review 4.  The ATR pathway: fine-tuning the fork.

Authors:  Renee D Paulsen; Karlene A Cimprich
Journal:  DNA Repair (Amst)       Date:  2007-05-24

5.  The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks.

Authors:  Katsuhiro Hanada; Magda Budzowska; Sally L Davies; Ellen van Drunen; Hideo Onizawa; H Berna Beverloo; Alex Maas; Jeroen Essers; Ian D Hickson; Roland Kanaar
Journal:  Nat Struct Mol Biol       Date:  2007-10-14       Impact factor: 15.369

6.  The Rad9-Hus1-Rad1 (9-1-1) clamp activates checkpoint signaling via TopBP1.

Authors:  Sinny Delacroix; Jill M Wagner; Masahiko Kobayashi; Ken-ichi Yamamoto; Larry M Karnitz
Journal:  Genes Dev       Date:  2007-06-15       Impact factor: 11.361

7.  Acetylation of lysine 56 of histone H3 catalyzed by RTT109 and regulated by ASF1 is required for replisome integrity.

Authors:  Junhong Han; Hui Zhou; Zhizhong Li; Rui-Ming Xu; Zhiguo Zhang
Journal:  J Biol Chem       Date:  2007-08-09       Impact factor: 5.157

8.  The annealing helicase HARP protects stalled replication forks.

Authors:  Jingsong Yuan; Gargi Ghosal; Junjie Chen
Journal:  Genes Dev       Date:  2009-09-30       Impact factor: 11.361

Review 9.  Interplay of replication checkpoints and repair proteins at stalled replication forks.

Authors:  Dana Branzei; Marco Foiani
Journal:  DNA Repair (Amst)       Date:  2007-03-26

10.  Yeast Rad5 protein required for postreplication repair has a DNA helicase activity specific for replication fork regression.

Authors:  András Blastyák; Lajos Pintér; Ildiko Unk; Louise Prakash; Satya Prakash; Lajos Haracska
Journal:  Mol Cell       Date:  2007-10-12       Impact factor: 17.970
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  23 in total

1.  The MMS22L-TONSL complex mediates recovery from replication stress and homologous recombination.

Authors:  Lara O'Donnell; Stephanie Panier; Jan Wildenhain; Johnny M Tkach; Abdallah Al-Hakim; Marie-Claude Landry; Cristina Escribano-Diaz; Rachel K Szilard; Jordan T F Young; Meagan Munro; Marella D Canny; Nadine K Kolas; Wei Zhang; Shane M Harding; Jarkko Ylanko; Megan Mendez; Michael Mullin; Thomas Sun; Bianca Habermann; Alessandro Datti; Robert G Bristow; Anne-Claude Gingras; Michael D Tyers; Grant W Brown; Daniel Durocher
Journal:  Mol Cell       Date:  2010-11-04       Impact factor: 17.970

2.  SMARCAL1 catalyzes fork regression and Holliday junction migration to maintain genome stability during DNA replication.

Authors:  Rémy Bétous; Aaron C Mason; Robert P Rambo; Carol E Bansbach; Akosua Badu-Nkansah; Bianca M Sirbu; Brandt F Eichman; David Cortez
Journal:  Genes Dev       Date:  2012-01-15       Impact factor: 11.361

3.  E3 ligase RFWD3 participates in replication checkpoint control.

Authors:  Zihua Gong; Junjie Chen
Journal:  J Biol Chem       Date:  2011-04-18       Impact factor: 5.157

Review 4.  Rescuing stalled or damaged replication forks.

Authors:  Joseph T P Yeeles; Jérôme Poli; Kenneth J Marians; Philippe Pasero
Journal:  Cold Spring Harb Perspect Biol       Date:  2013-05-01       Impact factor: 10.005

5.  Human DNA helicase B (HDHB) binds to replication protein A and facilitates cellular recovery from replication stress.

Authors:  Gulfem Dilek Guler; Hanjian Liu; Sivaraja Vaithiyalingam; Diana R Arnett; Elisabeth Kremmer; Walter J Chazin; Ellen Fanning
Journal:  J Biol Chem       Date:  2011-12-21       Impact factor: 5.157

Review 6.  Chromatin and the genome integrity network.

Authors:  Manolis Papamichos-Chronakis; Craig L Peterson
Journal:  Nat Rev Genet       Date:  2013-01       Impact factor: 53.242

Review 7.  Regulation of PCNA-protein interactions for genome stability.

Authors:  Niels Mailand; Ian Gibbs-Seymour; Simon Bekker-Jensen
Journal:  Nat Rev Mol Cell Biol       Date:  2013-04-18       Impact factor: 94.444

Review 8.  Synthetic lethality and cancer: cohesin and PARP at the replication fork.

Authors:  Nigel J O'Neil; Derek M van Pel; Philip Hieter
Journal:  Trends Genet       Date:  2013-01-18       Impact factor: 11.639

9.  Ewing Tumor-associated Antigen 1 Interacts with Replication Protein A to Promote Restart of Stalled Replication Forks.

Authors:  Sumin Feng; Yichao Zhao; Yixi Xu; Shaokai Ning; Wei Huo; Mei Hou; Ge Gao; Jianguo Ji; Rong Guo; Dongyi Xu
Journal:  J Biol Chem       Date:  2016-09-06       Impact factor: 5.157

10.  Schimke immunoosseous dysplasia: defining skeletal features.

Authors:  Kshamta B Hunter; Thomas Lücke; Jürgen Spranger; Sarah F Smithson; Harika Alpay; Jean-Luc André; Yumi Asakura; Radovan Bogdanovic; Dominique Bonneau; Robyn Cairns; Karlien Cransberg; Stefan Fründ; Helen Fryssira; David Goodman; Knut Helmke; Barbara Hinkelmann; Guiliana Lama; Petra Lamfers; Chantal Loirat; Silvia Majore; Christy Mayfield; Bertram F Pontz; Cristina Rusu; Jorge M Saraiva; Beate Schmidt; Lawrence Shoemaker; Sabine Sigaudy; Natasa Stajic; Doris Taha; Cornelius F Boerkoel
Journal:  Eur J Pediatr       Date:  2009-12-15       Impact factor: 3.183
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