| Literature DB >> 19830594 |
Lili Mao1, S Thangminlal Vaiphei, Tsutomu Shimazu, William M Schneider, Yuefeng Tang, Rajeswari Mani, Monica J Roth, Gaetano T Montelione, Masayori Inouye.
Abstract
At present, only 0.9% of PDB-deposited structures are of membrane proteins in spite of the fact that membrane proteins constitute approximately 30% of total proteins in most genomes from bacteria to humans. Here we address some of the major bottlenecks in the structural studies of membrane proteins and discuss the ability of the new technology, the Single-Protein Production system, to help solve these bottlenecks.Entities:
Mesh:
Substances:
Year: 2009 PMID: 19830594 PMCID: PMC4190415 DOI: 10.1007/s10969-009-9070-2
Source DB: PubMed Journal: J Struct Funct Genomics ISSN: 1345-711X