| Literature DB >> 19806155 |
Abstract
Adaptation to fluctuations in nutrient availability is a fact of life for single-celled organisms in the 'wild'. A decade ago our understanding of how bacteria adjust cell cycle parameters to accommodate changes in nutrient availability stemmed almost entirely from elegant physiological studies completed in the 1960s. In this Opinion article we summarize recent groundbreaking work in this area and discuss potential mechanisms by which nutrient availability and metabolic status are coordinated with cell growth, chromosome replication and cell division.Entities:
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Year: 2009 PMID: 19806155 PMCID: PMC2887316 DOI: 10.1038/nrmicro2202
Source DB: PubMed Journal: Nat Rev Microbiol ISSN: 1740-1526 Impact factor: 60.633