Literature DB >> 19795861

FePt nanoparticles as an Fe reservoir for controlled Fe release and tumor inhibition.

Chenjie Xu1, Zhenglong Yuan, Nathan Kohler, Jaemin Kim, Maureen A Chung, Shouheng Sun.   

Abstract

Chemically disordered face centered cubic (fcc) FePt nanoparticles (NPs) show the controlled release of Fe in low pH solution. The released Fe catalyzes H(2)O(2) decomposition into reactive oxygen species within cells, causing fast oxidation and deterioration of cellular membranes. Functionalized with luteinizing hormone-releasing hormone (LHRH) peptide via phospholipid, the fcc-FePt NPs can bind preferentially to the human ovarian cancer cell line (A2780) that overexpresses LHRH receptors and exhibit high toxicity to these tumor cells. In contrast, the fcc-FePt NPs pre-etched in the low pH (4.8) buffer solution show nonappreciable cytotoxicity. The work demonstrates that fcc-FePt NPs may function as a new type of agent for controlled cancer therapy.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19795861      PMCID： PMC2791709          DOI： 10.1021/ja905938a

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  31 in total

1.  C11-BODIPY(581/591), an oxidation-sensitive fluorescent lipid peroxidation probe: (micro)spectroscopic characterization and validation of methodology.

Authors:  Gregor P C Drummen; Lydia C M van Liebergen; Jos A F Op den Kamp; Jan A Post
Journal:  Free Radic Biol Med       Date:  2002-08-15       Impact factor: 7.376

Review 2.  Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean?

Authors:  Barry Halliwell; Matthew Whiteman
Journal:  Br J Pharmacol       Date:  2004-05       Impact factor: 8.739

3.  Magnetic resonance imaging of major histocompatibility class II expression in the renal medulla using immunotargeted superparamagnetic iron oxide nanoparticles.

Authors:  Kristi L Hultman; Anthony J Raffo; Adrienne L Grzenda; Paul E Harris; Truman R Brown; Stephen O'Brien
Journal:  ACS Nano       Date:  2008-03       Impact factor: 15.881

Review 4.  Magnetic nanoparticles in MR imaging and drug delivery.

Authors:  Conroy Sun; Jerry S H Lee; Miqin Zhang
Journal:  Adv Drug Deliv Rev       Date:  2008-04-10       Impact factor: 15.470

Review 5.  Superparamagnetic nanoparticles as targeted probes for diagnostic and therapeutic applications.

Authors:  Chenjie Xu; Shouheng Sun
Journal:  Dalton Trans       Date:  2009-05-01       Impact factor: 4.390

6.  Electro-oxidation of formic acid catalyzed by FePt nanoparticles.

Authors:  Wei Chen; Jaemin Kim; Shouheng Sun; Shaowei Chen
Journal:  Phys Chem Chem Phys       Date:  2006-05-25       Impact factor: 3.676

7.  Exchange-coupled nanocomposite magnets by nanoparticle self-assembly.

Authors:  Hao Zeng; Jing Li; J P Liu; Zhong L Wang; Shouheng Sun
Journal:  Nature       Date:  2002-11-28       Impact factor: 49.962

8.  Monodisperse FePt nanoparticles and ferromagnetic FePt nanocrystal superlattices

Authors: 
Journal:  Science       Date:  2000-03-17       Impact factor: 47.728

9.  FePt@CoS(2) yolk-shell nanocrystals as a potent agent to kill HeLa cells.

Authors:  Jinhao Gao; Gaolin Liang; Bei Zhang; Yi Kuang; Xixiang Zhang; Bing Xu
Journal:  J Am Chem Soc       Date:  2007-02-07       Impact factor: 15.419

10.  A common mechanism of cellular death induced by bactericidal antibiotics.

Authors:  Michael A Kohanski; Daniel J Dwyer; Boris Hayete; Carolyn A Lawrence; James J Collins
Journal:  Cell       Date:  2007-09-07       Impact factor: 41.582
View more
  31 in total

1.  Hybrid anisotropic nanostructures for dual-modal cancer imaging and image-guided chemo-thermo therapies.

Authors:  Ruiping Zhang; Kai Cheng; Alexander L Antaris; Xiaowei Ma; Min Yang; Sindhuja Ramakrishnan; Guifeng Liu; Alex Lu; Hongjie Dai; Mei Tian; Zhen Cheng
Journal:  Biomaterials       Date:  2016-07-02       Impact factor: 12.479

2.  Deciphering chemical order/disorder and material properties at the single-atom level.

Authors:  Yongsoo Yang; Chien-Chun Chen; M C Scott; Colin Ophus; Rui Xu; Alan Pryor; Li Wu; Fan Sun; Wolfgang Theis; Jihan Zhou; Markus Eisenbach; Paul R C Kent; Renat F Sabirianov; Hao Zeng; Peter Ercius; Jianwei Miao
Journal:  Nature       Date:  2017-02-01       Impact factor: 49.962

3.  Structural and Magnetic Characterization of Superparamagnetic Iron Platinum Nanoparticle Contrast Agents for Magnetic Resonance Imaging.

Authors:  Robert M Taylor; Dale L Huber; Todd C Monson; Victor Esch; Laurel O Sillerud
Journal:  J Vac Sci Technol B Nanotechnol Microelectron       Date:  2012-03

4.  Structural and magnetic characterization of superparamagnetic iron platinum nanoparticle contrast agents for magnetic resonance imaging.

Authors:  Robert M Taylor; Dale L Huber; Todd C Monson; Victor Esch; Laurel O Sillerud
Journal:  J Vac Sci Technol B Nanotechnol Microelectron       Date:  2012-03-05

5.  Fe5C2 nanoparticles with high MRI contrast enhancement for tumor imaging.

Authors:  Wei Tang; Zipeng Zhen; Ce Yang; Luning Wang; Taku Cowger; Hongmin Chen; Trever Todd; Khan Hekmatyar; Qun Zhao; Yanglong Hou; Jin Xie
Journal:  Small       Date:  2013-12-18       Impact factor: 13.281

Review 6.  Monodisperse magnetic nanoparticles for theranostic applications.

Authors:  Don Ho; Xiaolian Sun; Shouheng Sun
Journal:  Acc Chem Res       Date:  2011-06-10       Impact factor: 22.384

Review 7.  Nanoparticle-based monitoring of cell therapy.

Authors:  Chenjie Xu; Luye Mu; Isaac Roes; David Miranda-Nieves; Matthias Nahrendorf; James A Ankrum; Weian Zhao; Jeffrey M Karp
Journal:  Nanotechnology       Date:  2011-11-21       Impact factor: 3.874

8.  Multifunctional iron platinum stealth immunomicelles: targeted detection of human prostate cancer cells using both fluorescence and magnetic resonance imaging.

Authors:  Robert M Taylor; Dale L Huber; Todd C Monson; Abdul-Mehdi S Ali; Marco Bisoffi; Laurel O Sillerud
Journal:  J Nanopart Res       Date:  2011-10-01       Impact factor: 2.253

9.  Functional ferritin nanoparticles for biomedical applications.

Authors:  Zhantong Wang; Haiyan Gao; Yang Zhang; Gang Liu; Gang Niu; Xiaoyuan Chen
Journal:  Front Chem Sci Eng       Date:  2017-02-15       Impact factor: 4.204

10.  Engineered biocompatible nanoparticles for in vivo imaging applications.

Authors:  Shu Chen; Lijun Wang; Suzanne L Duce; Stuart Brown; Stephen Lee; Andreas Melzer; Alfred Cuschieri; Pascal André
Journal:  J Am Chem Soc       Date:  2010-10-27       Impact factor: 15.419
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.