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Literature DB >> 24352976

Fe5C2 nanoparticles with high MRI contrast enhancement for tumor imaging.

Wei Tang¹, Zipeng Zhen, Ce Yang, Luning Wang, Taku Cowger, Hongmin Chen, Trever Todd, Khan Hekmatyar, Qun Zhao, Yanglong Hou, Jin Xie.

Abstract

An ancient material for magnetic resonance (MR) imaging: For the first time, Fe5C2 is prepared as colloidal stable nanoparticles with good aqueous stability. The nanoparticles boast strong magnetization, excellent chemical inertness, low toxicity, and one of the highest r2 relaxivities reported to date. These nanoparticles hold great potential in MR imaging as well as in other biomedical areas.

Entities: CellLine Chemical Disease Gene Species

Keywords: integrins; iron carbides; magnetic properties; magnetic resonance imaging; nanoparticles

Mesh：

Substances：

Year: 2013 PMID： 24352976 PMCID： PMC6398947 DOI： 10.1002/smll.201303263

Source DB: PubMed Journal: Small ISSN： 1613-6810 Impact factor: 13.281

24 in total

1. Nanoscale size effect of magnetic nanocrystals and their utilization for cancer diagnosis via magnetic resonance imaging.

Authors: Young-Wook Jun; Yong-Min Huh; Jin-Sil Choi; Jae-Hyun Lee; Ho-Taek Song; Sungjun Kim; Sarah Yoon; Kyung-Sup Kim; Jeon-Soo Shin; Jin-Suck Suh; Jinwoo Cheon
Journal: J Am Chem Soc Date: 2005-04-27 Impact factor: 15.419

2. A general strategy for synthesizing FePt nanowires and nanorods.

Authors: Chao Wang; Yanglong Hou; Jaemin Kim; Shouheng Sun
Journal: Angew Chem Int Ed Engl Date: 2007 Impact factor: 15.336

3. Synergistically integrated nanoparticles as multimodal probes for nanobiotechnology.

Authors: Jinwoo Cheon; Jae-Hyun Lee
Journal: Acc Chem Res Date: 2008-12 Impact factor: 22.384

4. Synthesis and stabilization of monodisperse Fe nanoparticles.

Authors: Sheng Peng; Chao Wang; Jin Xie; Shouheng Sun
Journal: J Am Chem Soc Date: 2006-08-23 Impact factor: 15.419

5. In vivo magnetic resonance detection of cancer by using multifunctional magnetic nanocrystals.

Authors: Yong-Min Huh; Young-wook Jun; Ho-Taek Song; Sungjun Kim; Jin-sil Choi; Jae-Hyun Lee; Sarah Yoon; Kyung-sup Kim; Jeon-Soo Shin; Jin-Suck Suh; Jinwoo Cheon
Journal: J Am Chem Soc Date: 2005-09-07 Impact factor: 15.419

6. FePt@CoS(2) yolk-shell nanocrystals as a potent agent to kill HeLa cells.

Authors: Jinhao Gao; Gaolin Liang; Bei Zhang; Yi Kuang; Xixiang Zhang; Bing Xu
Journal: J Am Chem Soc Date: 2007-02-07 Impact factor: 15.419

7. Thermally cross-linked superparamagnetic iron oxide nanoparticles: synthesis and application as a dual imaging probe for cancer in vivo.

Authors: Haerim Lee; Mi Kyung Yu; Sangjin Park; Sungmin Moon; Jung Jun Min; Yong Yeon Jeong; Hae-Won Kang; Sangyong Jon
Journal: J Am Chem Soc Date: 2007-09-25 Impact factor: 15.419

8. Dopamine as a robust anchor to immobilize functional molecules on the iron oxide shell of magnetic nanoparticles.

Authors: Chenjie Xu; Keming Xu; Hongwei Gu; Rongkun Zheng; Hui Liu; Xixiang Zhang; Zhihong Guo; Bing Xu
Journal: J Am Chem Soc Date: 2004-08-18 Impact factor: 15.419

9. PET/MRI dual-modality tumor imaging using arginine-glycine-aspartic (RGD)-conjugated radiolabeled iron oxide nanoparticles.

Authors: Ha-Young Lee; Zibo Li; Kai Chen; Andrew R Hsu; Chenjie Xu; Jin Xie; Shouheng Sun; Xiaoyuan Chen
Journal: J Nucl Med Date: 2008-07-16 Impact factor: 10.057

Fe5C2 nanoparticles with high MRI contrast enhancement for tumor imaging.

1. Nanoscale size effect of magnetic nanocrystals and their utilization for cancer diagnosis via magnetic resonance imaging.

2. A general strategy for synthesizing FePt nanowires and nanorods.

3. Synergistically integrated nanoparticles as multimodal probes for nanobiotechnology.

4. Synthesis and stabilization of monodisperse Fe nanoparticles.

5. In vivo magnetic resonance detection of cancer by using multifunctional magnetic nanocrystals.

6. FePt@CoS(2) yolk-shell nanocrystals as a potent agent to kill HeLa cells.

7. Thermally cross-linked superparamagnetic iron oxide nanoparticles: synthesis and application as a dual imaging probe for cancer in vivo.

8. Dopamine as a robust anchor to immobilize functional molecules on the iron oxide shell of magnetic nanoparticles.

9. PET/MRI dual-modality tumor imaging using arginine-glycine-aspartic (RGD)-conjugated radiolabeled iron oxide nanoparticles.

10. Monodisperse MFe2O4 (M = Fe, Co, Mn) nanoparticles.

1. Red Blood Cell-Facilitated Photodynamic Therapy for Cancer Treatment.

2. Casein-Coated Fe5C2 Nanoparticles with Superior r2 Relaxivity for Liver-Specific Magnetic Resonance Imaging.

3. Environmental STEM Study of the Oxidation Mechanism for Iron and Iron Carbide Nanoparticles.

4. An ultra-sensitive T ₂-weighted MR contrast agent based on Gd³⁺ ion chelated Fe₃O₄ nanoparticles.

Review 5. Surface impact on nanoparticle-based magnetic resonance imaging contrast agents.