Literature DB >> 20449070

Superparamagnetic nanoparticles as targeted probes for diagnostic and therapeutic applications.

Chenjie Xu1, Shouheng Sun.   

Abstract

Superparamagnetic nanoparticles (NPs) have been attractive for medical diagnostics and therapeutics due to their unique magnetic properties and their ability to interact with various biomolecules of interest. The solution phase based chemical synthesis provides a near precise control on NP size, and monodisperse magnetic NPs with standard deviation in diameter of less than 10% are now routinely available. Upon controlled surface functionalization and coupling with fragments of DNA strands, proteins, peptides or antibodies, these NPs can be well-dispersed in biological solutions and used for drug delivery, magnetic separation, magnetic resonance imaging contrast enhancement and magnetic fluid hyperthermia. This Perspective reviews the common syntheses and controlled surface functionalization of monodisperse Fe(3)O(4)-based superparamagnetic NPs. It further outlines the exciting application potentials of these NPs in magnetic resonance imaging and drug delivery.

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Year:  2009        PMID： 20449070      PMCID： PMC2867062          DOI： 10.1039/b900272n

Source DB:  PubMed          Journal:  Dalton Trans        ISSN： 1477-9226            Impact factor:   4.390


  64 in total

1.  Magnetic resonance of a dextran-coated magnetic fluid intravenously administered in mice.

Authors:  L M Lacava; Z G Lacava; M F Da Silva; O Silva; S B Chaves; R B Azevedo; F Pelegrini; C Gansau; N Buske; D Sabolovic; P C Morais
Journal:  Biophys J       Date:  2001-05       Impact factor: 4.033

Review 2.  Drug-polymer conjugates containing acid-cleavable bonds.

Authors:  F Kratz; U Beyer; M T Schütte
Journal:  Crit Rev Ther Drug Carrier Syst       Date:  1999       Impact factor: 4.889

3.  Synthesis of highly crystalline and monodisperse maghemite nanocrystallites without a size-selection process.

Authors:  T Hyeon; S S Lee; J Park; Y Chung; H B Na
Journal:  J Am Chem Soc       Date:  2001-12-26       Impact factor: 15.419

4.  Polymeric systems for controlled drug release.

Authors:  K E Uhrich; S M Cannizzaro; R S Langer; K M Shakesheff
Journal:  Chem Rev       Date:  1999-11-10       Impact factor: 60.622

Review 5.  Long-circulating and target-specific nanoparticles: theory to practice.

Authors:  S M Moghimi; A C Hunter; J C Murray
Journal:  Pharmacol Rev       Date:  2001-06       Impact factor: 25.468

Review 6.  Untangling the ErbB signalling network.

Authors:  Y Yarden; M X Sliwkowski
Journal:  Nat Rev Mol Cell Biol       Date:  2001-02       Impact factor: 94.444

7.  Size-dependent extravasation and interstitial localization of polyethyleneglycol liposomes in solid tumor-bearing mice.

Authors:  O Ishida; K Maruyama; K Sasaki; M Iwatsuru
Journal:  Int J Pharm       Date:  1999-11-10       Impact factor: 5.875

8.  Hyperthermia enables tumor-specific nanoparticle delivery: effect of particle size.

Authors:  G Kong; R D Braun; M W Dewhirst
Journal:  Cancer Res       Date:  2000-08-15       Impact factor: 12.701

Review 9.  Nanoparticles in cancer therapy and diagnosis.

Authors:  Irène Brigger; Catherine Dubernet; Patrick Couvreur
Journal:  Adv Drug Deliv Rev       Date:  2002-09-13       Impact factor: 15.470

10.  Size-controlled synthesis of magnetite nanoparticles.

Authors:  Shouheng Sun; Hao Zeng
Journal:  J Am Chem Soc       Date:  2002-07-17       Impact factor: 15.419
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  21 in total

Review 1.  Development of mesoporous silica nanomaterials as a vehicle for anticancer drug delivery.

Authors:  Rolando E Yanes; Fuyuhiko Tamanoi
Journal:  Ther Deliv       Date:  2012-03

Review 2.  Nanoparticle-based monitoring of cell therapy.

Authors:  Chenjie Xu; Luye Mu; Isaac Roes; David Miranda-Nieves; Matthias Nahrendorf; James A Ankrum; Weian Zhao; Jeffrey M Karp
Journal:  Nanotechnology       Date:  2011-11-21       Impact factor: 3.874

3.  Tracking mesenchymal stem cells with iron oxide nanoparticle loaded poly(lactide-co-glycolide) microparticles.

Authors:  Chenjie Xu; David Miranda-Nieves; James A Ankrum; Mads Emil Matthiesen; Joseph A Phillips; Isaac Roes; Gregory R Wojtkiewicz; Vikram Juneja; Jens Roat Kultima; Weian Zhao; Praveen Kumar Vemula; Charles P Lin; Matthias Nahrendorf; Jeffrey M Karp
Journal:  Nano Lett       Date:  2012-07-12       Impact factor: 11.189

4.  Combining in Vitro Diagnostics with in Vivo Imaging for Earlier Detection of Pancreatic Ductal Adenocarcinoma: Challenges and Solutions.

Authors:  Paul F Laeseke; Ru Chen; R Brooke Jeffrey; Teresa A Brentnall; Jürgen K Willmann
Journal:  Radiology       Date:  2015-12       Impact factor: 11.105

5.  Magnetically-coated silica nanospheres for dual-mode imaging at low ultrasound frequency.

Authors:  Fernanda Chiriacò; Giulia Soloperto; Antonio Greco; Francesco Conversano; Andrea Ragusa; Luca Menichetti; Sergio Casciaro
Journal:  World J Radiol       Date:  2013-11-28

6.  FePt nanoparticles as an Fe reservoir for controlled Fe release and tumor inhibition.

Authors:  Chenjie Xu; Zhenglong Yuan; Nathan Kohler; Jaemin Kim; Maureen A Chung; Shouheng Sun
Journal:  J Am Chem Soc       Date:  2009-10-28       Impact factor: 15.419

7.  Conjugating Methotrexate to magnetite (Fe(3)O(4)) nanoparticles via trichloro-s-triazine.

Authors:  Kaylie L Young; Chenjie Xu; Jin Xie; Shouheng Sun
Journal:  J Mater Chem       Date:  2009-01-01

8.  Microfluidic synthesis of microfibers for magnetic-responsive controlled drug release and cell culture.

Authors:  Yung-Sheng Lin; Keng-Shiang Huang; Chih-Hui Yang; Chih-Yu Wang; Yuh-Shyong Yang; Hsiang-Chen Hsu; Yu-Ju Liao; Chia-Wen Tsai
Journal:  PLoS One       Date:  2012-03-28       Impact factor: 3.240

9.  Iron oxide nanoparticle-micelles (ION-micelles) for sensitive (molecular) magnetic particle imaging and magnetic resonance imaging.

Authors:  Lucas W E Starmans; Dirk Burdinski; Nicole P M Haex; Rik P M Moonen; Gustav J Strijkers; Klaas Nicolay; Holger Grüll
Journal:  PLoS One       Date:  2013-02-20       Impact factor: 3.240

10.  Antitumor effect and toxicity of free rhodium (II) citrate and rhodium (II) citrate-loaded maghemite nanoparticles in mice bearing breast cancer.

Authors:  Marcella Lemos Brettas Carneiro; Raphael C A Peixoto; Graziela A Joanitti; Ricardo G S Oliveira; Luis A M Telles; Ana L Miranda-Vilela; Anamélia L Bocca; Leonora M S Vianna; Izabel C R da Silva; Aparecido R de Souza; Zulmira G M Lacava; Sônia N Báo
Journal:  J Nanobiotechnology       Date:  2013-02-16       Impact factor: 10.435
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