Literature DB >> 19774544

The effect of electrostatic shielding on H tunneling in R67 dihydrofolate reductase.

Atsushi Yahashiri1, Guy Nimrod, Nir Ben-Tal, Elizabeth E Howell, Amnon Kohen.   

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Year:  2009        PMID： 19774544      PMCID： PMC2824884          DOI： 10.1002/cbic.200900451

Source DB:  PubMed          Journal:  Chembiochem        ISSN： 1439-4227            Impact factor:   3.164


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  18 in total

1.  Atomic description of an enzyme reaction dominated by proton tunneling.

Authors:  Laura Masgrau; Anna Roujeinikova; Linus O Johannissen; Parvinder Hothi; Jaswir Basran; Kara E Ranaghan; Adrian J Mulholland; Michael J Sutcliffe; Nigel S Scrutton; David Leys
Journal:  Science       Date:  2006-04-14       Impact factor: 47.728

2.  The role of enzyme dynamics and tunnelling in catalysing hydride transfer: studies of distal mutants of dihydrofolate reductase.

Authors:  Lin Wang; Nina M Goodey; Stephen J Benkovic; Amnon Kohen
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2006-08-29       Impact factor: 6.237

3.  Effects of a distal mutation on active site chemistry.

Authors:  Lin Wang; Scott Tharp; Tzvia Selzer; Stephen J Benkovic; Amnon Kohen
Journal:  Biochemistry       Date:  2006-02-07       Impact factor: 3.162

4.  Coordinated effects of distal mutations on environmentally coupled tunneling in dihydrofolate reductase.

Authors:  Lin Wang; Nina M Goodey; Stephen J Benkovic; Amnon Kohen
Journal:  Proc Natl Acad Sci U S A       Date:  2006-10-10       Impact factor: 11.205

5.  Enzyme dynamics and hydrogen tunnelling in a thermophilic alcohol dehydrogenase.

Authors:  A Kohen; R Cannio; S Bartolucci; J P Klinman
Journal:  Nature       Date:  1999-06-03       Impact factor: 49.962

6.  High expression in Escherichia coli of the gene coding for dihydrofolate reductase of the extremely halophilic archaebacterium Haloferax volcanii. Reconstitution of the active enzyme and mutation studies.

Authors:  O Blecher; S Goldman; M Mevarech
Journal:  Eur J Biochem       Date:  1993-08-15

7.  Role of ionic interactions in ligand binding and catalysis of R67 dihydrofolate reductase.

Authors:  Stephanie N Hicks; R Derike Smiley; J Bradley Hamilton; Elizabeth E Howell
Journal:  Biochemistry       Date:  2003-09-16       Impact factor: 3.162

8.  Driving force analysis of proton tunnelling across a reactivity series for an enzyme-substrate complex.

Authors:  Parvinder Hothi; Sam Hay; Anna Roujeinikova; Michael J Sutcliffe; Michael Lee; David Leys; Paul M Cullis; Nigel S Scrutton
Journal:  Chembiochem       Date:  2008-11-24       Impact factor: 3.164

9.  Mutagenesis of morphinone reductase induces multiple reactive configurations and identifies potential ambiguity in kinetic analysis of enzyme tunneling mechanisms.

Authors:  Christopher R Pudney; Sam Hay; Jiayun Pang; Claire Costello; David Leys; Michael J Sutcliffe; Nigel S Scrutton
Journal:  J Am Chem Soc       Date:  2007-10-16       Impact factor: 15.419

10.  Crystal structure of a type II dihydrofolate reductase catalytic ternary complex.

Authors:  Joseph M Krahn; Michael R Jackson; Eugene F DeRose; Elizabeth E Howell; Robert E London
Journal:  Biochemistry       Date:  2007-12-04       Impact factor: 3.162
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  2 in total

1.  Update 1 of: Tunneling and dynamics in enzymatic hydride transfer.

Authors:  Zachary D Nagel; Judith P Klinman
Journal:  Chem Rev       Date:  2010-12-08       Impact factor: 60.622

2.  Temperature-Dependent Kinetic Isotope Effects in R67 Dihydrofolate Reductase from Path-Integral Simulations.

Authors:  Anil R Mhashal; Dan Thomas Major
Journal:  J Phys Chem B       Date:  2021-02-01       Impact factor: 2.991
  2 in total

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