Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Induction of glutamine synthetase by 8-bromo cyclic AMP in primary cultures of rat brain astrocytes.

Literature DB >> 1977090

Induction of glutamine synthetase by 8-bromo cyclic AMP in primary cultures of rat brain astrocytes.

Abstract

Glutamine synthetase (GS) is the key enzyme in cerebral glutamine production. Understanding the regulation of the expression of GS is important for definition of the control of glutamine metabolism in brain. Therefore, we studied the control of GS expression by 8-bromo cyclic AMP in primary cultures of astrocytes prepared from brains of neonatal rats. GS activity was increased by 8-bromo cyclic AMP in a dose- and time-dependent manner. This increase was associated with a corresponding increase in the steady-state level of GS mRNA.

Entities: Chemical Gene Species

Mesh：

Substances：

Year: 1990 PMID： 1977090 DOI： 10.1007/bf00973746

Source DB: PubMed Journal: Neurochem Res ISSN： 0364-3190 Impact factor: 3.996

17 in total

1. The ontogeny and localization of glutamine synthetase gene expression in rat brain.

Authors: K M Mearow; J F Mill; L Vitkovic
Journal: Brain Res Mol Brain Res Date: 1989-12

2. Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

Authors: P S Thomas
Journal: Proc Natl Acad Sci U S A Date: 1980-09 Impact factor: 11.205

3. The hormonal regulation of gene expression of glial markers: glutamine synthetase and glycerol phosphate dehydrogenase in primary cultures of rat brain and in C6 cell line.

Authors: S Kumar; E Holmes; S Scully; B W Birren; R H Wilson; J de Vellis
Journal: J Neurosci Res Date: 1986 Impact factor: 4.164

1. Effect of dibutyryl cyclic AMP and dexamethasone on glutamine synthetase gene expression in rat astrocytes in culture.

Authors: M J Jackson; H R Zielke; S R Max
Journal: Neurochem Res Date: 1995-02 Impact factor: 3.996

2. Effect of 8-bromo-cAMP and dexamethasone on glutamate metabolism in rat astrocytes.

Authors: H R Zielke; J T Tildon; M E Landry; S R Max
Journal: Neurochem Res Date: 1990-11 Impact factor: 3.996

2 in total

Induction of glutamine synthetase by 8-bromo cyclic AMP in primary cultures of rat brain astrocytes.

1. The ontogeny and localization of glutamine synthetase gene expression in rat brain.

2. Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

3. The hormonal regulation of gene expression of glial markers: glutamine synthetase and glycerol phosphate dehydrogenase in primary cultures of rat brain and in C6 cell line.

4. "A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity". Addendum.

5. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.

6. Glutamine synthetase: glial localization in brain.

7. Induction of glutamine synthetase by dibutyryl cyclic AMP in C-6 glioma cells.

8. Identification of procollagen mRNAs transferred to diazobenzyloxymethyl paper from formaldehyde agarose gels.

9. Glutamine synthetase mRNA in cultured 3T3-L1 adipocytes. Complexity, content and hormonal regulation.

10. Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue.

1. Effect of dibutyryl cyclic AMP and dexamethasone on glutamine synthetase gene expression in rat astrocytes in culture.

2. Effect of 8-bromo-cAMP and dexamethasone on glutamate metabolism in rat astrocytes.