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Literature DB >> 19764760

Quadrupole-central-transition 17O NMR spectroscopy of protein-ligand complexes in solution.

Abstract

We report the first (17)O quadrupole-central-transition (QCT) NMR spectroscopic study of protein-ligand complexes in solution. This work shows that it is possible to obtain high resolution (17)O NMR spectra for (17)O-labeled ligands bound to proteins. At high magnetic fields such as 21.14 T, this (17)O QCT NMR approach should be applicable to studies of all oxygen-containing functional groups in large proteins (>30 kDa).

Entities: Chemical

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Year: 2009 PMID： 19764760 DOI： 10.1021/ja906881n

Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419

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Cited

4 in total

1. ¹⁷ O NMR Studies of Yeast Ubiquitin in Aqueous Solution and in the Solid State.

Authors: Binyang Lin; Ivan Hung; Zhehong Gan; Po-Hsiu Chien; Holly L Spencer; Steven P Smith; Gang Wu
Journal: Chembiochem Date: 2020-11-06 Impact factor: 3.164

2. NMR spectroscopy up to 35.2T using a series-connected hybrid magnet.

Authors: Zhehong Gan; Ivan Hung; Xiaoling Wang; Joana Paulino; Gang Wu; Ilya M Litvak; Peter L Gor'kov; William W Brey; Pietro Lendi; Jeffrey L Schiano; Mark D Bird; Iain R Dixon; Jack Toth; Gregory S Boebinger; Timothy A Cross
Journal: J Magn Reson Date: 2017-08-24 Impact factor: 2.229

3. Solid-state ¹⁷O NMR study of α-d-glucose: exploring new frontiers in isotopic labeling, sensitivity enhancement, and NMR crystallography.

Authors: Jiahui Shen; Victor Terskikh; Jochem Struppe; Alia Hassan; Martine Monette; Ivan Hung; Zhehong Gan; Andreas Brinkmann; Gang Wu
Journal: Chem Sci Date: 2022-01-03 Impact factor: 9.825

Review 4. ¹⁷O NMR Spectroscopy: A Novel Probe for Characterizing Protein Structure and Folding.

Authors: Srinivasan Muniyappan; Yuxi Lin; Young-Ho Lee; Jin Hae Kim
Journal: Biology (Basel) Date: 2021-05-21

4 in total

Quadrupole-central-transition 17O NMR spectroscopy of protein-ligand complexes in solution.

1. 17 O NMR Studies of Yeast Ubiquitin in Aqueous Solution and in the Solid State.

2. NMR spectroscopy up to 35.2T using a series-connected hybrid magnet.

3. Solid-state 17O NMR study of α-d-glucose: exploring new frontiers in isotopic labeling, sensitivity enhancement, and NMR crystallography.

Review 4. 17O NMR Spectroscopy: A Novel Probe for Characterizing Protein Structure and Folding.

1. ¹⁷ O NMR Studies of Yeast Ubiquitin in Aqueous Solution and in the Solid State.

3. Solid-state ¹⁷O NMR study of α-d-glucose: exploring new frontiers in isotopic labeling, sensitivity enhancement, and NMR crystallography.

Review 4. ¹⁷O NMR Spectroscopy: A Novel Probe for Characterizing Protein Structure and Folding.