Literature DB >> 19761094

Analysis of the physical interactions of therapeutic proton beams in water with the use of Geant4 Monte Carlo calculations.

Zdenek Morávek1, Ludwig Bogner.   

Abstract

The processes that occur when protons traverse a medium are investigated theoretically for a full therapeutic range of energies [20 MeV, 220 MeV]. The investigation is undertaken using the Geant4 toolkit for water medium. The beam is simulated only inside the phantom, effects of beamline are included in the overall beam properties as lateral width and momentum bandwidth. Every energy deposition is catalogued according to the particle and the process that caused it. The catalogued depositions are analysed statistically. There are only few important processes such as proton ionisation and nuclear scattering (elastic/inelastic) that constitute the main features of the energy distribution. At the same time processes concerning electrons are used very often without obvious effect to the result. Such processes can be therefore approximated in the simulation codes in order to improve the performance of the code. Neutron depositions are most important before the Bragg peak, still they are by an order of magnitude smaller than those of protons. In the region behind the Bragg peak only a small number of neutrons is created in the simulation and their energy contribution through secondary protons is by orders smaller than the effect of proton-produced secondary protons within the Bragg peak. Hence, the effects of neutrons created in the calculation volume can be neglected.

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Year:  2009        PMID: 19761094     DOI: 10.1016/j.zemedi.2009.04.006

Source DB:  PubMed          Journal:  Z Med Phys        ISSN: 0939-3889            Impact factor:   4.820


  4 in total

1.  The determination of a dose deposited in reference medium due to (p,n) reaction occurring during proton therapy.

Authors:  Anna Dawidowska; Monika Paluch Ferszt; Adam Konefał
Journal:  Rep Pract Oncol Radiother       Date:  2014-05-05

2.  Influence of secondary neutrons induced by proton radiotherapy for cancer patients with implantable cardioverter defibrillators.

Authors:  Takayuki Hashimoto; Tomonori Isobe; Haruko Hashii; Hiroaki Kumada; Hiroshi Tada; Toshiyuki Okumura; Koji Tsuboi; Takeji Sakae; Kazutaka Aonuma; Hideyuki Sakurai
Journal:  Radiat Oncol       Date:  2012-01-29       Impact factor: 3.481

3.  Radiation promotes colorectal cancer initiation and progression by inducing senescence-associated inflammatory responses.

Authors:  S B Kim; R G Bozeman; A Kaisani; W Kim; L Zhang; J A Richardson; W E Wright; J W Shay
Journal:  Oncogene       Date:  2015-10-19       Impact factor: 9.867

Review 4.  The impact of particle radiotherapy on the functioning of cardiac implantable electronic devices: a systematic review of in vitro and in vivo studies according to PICO criteria.

Authors:  Amelia Barcellini; Veronica Dusi; Alfredo Mirandola; Sara Ronchi; Giulia Riva; Francesca Dal Mas; Maurizio Massaro; Viviana Vitolo; Mario Ciocca; Roberto Rordorf; Ester Orlandi
Journal:  Radiol Med       Date:  2022-07-24       Impact factor: 6.313

  4 in total

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