Literature DB >> 19754128

Cassiarins C-E, antiplasmodial alkaloids from the flowers of Cassia siamea.

Shiori Oshimi1, Jun Deguchi, Yusuke Hirasawa, Wiwied Ekasari, Aty Widyawaruyanti, Tutik Sri Wahyuni, Noor Cholies Zaini, Osamu Shirota, Hiroshi Morita.   

Abstract

Three new alkaloids, cassiarins C-E (1-3), and a new chromone, 10,11-dihydroanhydrobarakol (4), which showed moderate antiplasmodial activity against Plasmodium falciparum 3D7, were isolated from flowers of Cassia siamea, and the structures of 1-4 were elucidated by 2D NMR analysis and chemical transformation. Cassiarin D (2) was a dimeric compound consisting of 5-acetonyl-7-hydroxy-2-methylchromone and cassiarin C (1), and cassiarin E (3) was a dimer of cassiarins A and C (1).

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Year:  2009        PMID： 19754128     DOI： 10.1021/np9004213

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  8 in total

1.  Sanjecumins A and B: new limonoids from Sandoricum koetjape.

Authors:  Yuta Nagakura; Alfarius Eko Nugroho; Yusuke Hirasawa; Takahiro Hosoya; Abdul Rahman; Idha Kusumawati; Noor Cholies Zaini; Hiroshi Morita
Journal:  J Nat Med       Date:  2012-06-22       Impact factor: 2.343

2.  Antiplasmodial indole alkaloids from Leuconotis griffithii.

Authors:  Alfarius E Nugroho; Yusuke Hirasawa; Wong Chin Piow; Toshio Kaneda; A Hamid A Hadi; Osamu Shirota; Wiwied Ekasari; Aty Widyawaruyanti; Hiroshi Morita
Journal:  J Nat Med       Date:  2011-08-10       Impact factor: 2.343

3.  Antiplasmodial activity of selected medicinal plants used to treat malaria in Ghana.

Authors:  Gustav Komlaga; Sandrine Cojean; Rita A Dickson; Mehdi A Beniddir; Soulaf Suyyagh-Albouz; Merlin L K Mensah; Christian Agyare; Pierre Champy; Philippe M Loiseau
Journal:  Parasitol Res       Date:  2016-05-13       Impact factor: 2.289

4.  Leucophyllinines A and B, bisindole alkaloids from Leuconotis eugeniifolia.

Authors:  Yiming Tang; Alfarius Eko Nugroho; Yusuke Hirasawa; Takahiro Tougan; Toshihiro Horii; A Hamid A Hadi; Hiroshi Morita
Journal:  J Nat Med       Date:  2019-03-25       Impact factor: 2.343

5.  Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids.

Authors:  Yijun Yan; Jing Yang; Zhiyin Yu; Mingming Yu; Ya-Tuan Ma; Li Wang; Can Su; Jianying Luo; Geoffrey P Horsman; Sheng-Xiong Huang
Journal:  Nat Commun       Date:  2016-10-07       Impact factor: 14.919

6.  Inverse docking based screening and identification of protein targets for Cassiarin alkaloids against Plasmodium falciparum.

Authors:  Arvind Negi; Nitisha Bhandari; Bharti Rajesh Kumar Shyamlal; Sandeep Chaudhary
Journal:  Saudi Pharm J       Date:  2018-02-02       Impact factor: 4.330

7.  In-silico screening for anti-Zika virus phytochemicals.

Authors:  Kendall G Byler; Ifedayo Victor Ogungbe; William N Setzer
Journal:  J Mol Graph Model       Date:  2016-08-28       Impact factor: 2.518

Review 8.  A Review of Recent Studies on the Antioxidant and Anti-Infectious Properties of Senna Plants.

Authors:  Mohammed M Alshehri; Cristina Quispe; Jesús Herrera-Bravo; Javad Sharifi-Rad; Sena Tutuncu; Elif Feyza Aydar; Cansu Topkaya; Zehra Mertdinc; Beraat Ozcelik; Mahima Aital; N V Anil Kumar; Natallia Lapava; Jovana Rajkovic; Andrea Ertani; Silvana Nicola; Prabhakar Semwal; Sakshi Painuli; Carlos González-Contreras; Miquel Martorell; Monica Butnariu; Iulia Cristina Bagiu; Radu Vasile Bagiu; Mrunal D Barbhai; Manoj Kumar; Sevgi Durna Daştan; Daniela Calina; William C Cho
Journal:  Oxid Med Cell Longev       Date:  2022-02-04       Impact factor: 6.543
  8 in total

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