Literature DB >> 19724044

Life-science research within US academic medical centers.

Darren E Zinner1, Eric G Campbell.   

Abstract

CONTEXT: Besides the generic "basic" vs "applied" labels, little information is known about the types of life-science research conducted within academic medical centers (AMCs).
OBJECTIVE: To determine the relative proportion, characteristics, funding, and productivity of AMC faculty by the type of research they conduct.
DESIGN: Mailed survey conducted in 2007 of 3080 life-science faculty at the 50 universities with medical schools that received the most funding from the National Institutes of Health in 2004. Response rate was 74%. SETTING AND PARTICIPANTS: Research faculty affiliated with a medical school or teaching hospital, representing 77% of respondents (n = 1663). MAIN OUTCOME MEASURES: Type of research (basic, translational, clinical trials, health services research/clinical epidemiology, multimode, other), total funding, industry funding, publications, professional activities, patenting behavior, and industry relationships.
RESULTS: Among AMC research faculty, 33.6% exclusively conducted basic science research as principal investigators compared with translational researchers (9.1%), clinical trial investigators (7.1%), and health services researchers/clinical epidemiologists (9.0%). While principal investigators garnered a mean of $410,755 in total annual research funding, 22.1% of all AMC research faculty were unsponsored, a proportion that ranged from 11.5% for basic science researchers to 46.8% for health services researchers (P < .001). The average AMC faculty member received $33,417 in industry-sponsored funding, with most of this money concentrated among clinical trial ($110,869) and multimode ($59,916) principal investigators. Translational (61.3%), clinical trial (67.3%), and multimode (70.9%) researchers were significantly more likely than basic science researchers (41.9%) to report a relationship with industry and that these relationships contributed to their most important scientific work (P < .05 for all comparisons).
CONCLUSION: The research function of AMCs is active and diverse, incorporating a substantial proportion of faculty who are conducting research and publishing without sponsorship.

Entities:  

Mesh:

Year:  2009        PMID: 19724044      PMCID: PMC3772727          DOI: 10.1001/jama.2009.1265

Source DB:  PubMed          Journal:  JAMA        ISSN: 0098-7484            Impact factor:   56.272


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