Literature DB >> 19723585

Bacteremia with a large clostridial toxin-negative, binary toxin-positive strain of Clostridium difficile.

Briony Elliott1, Robert Reed, Barbara J Chang, Thomas V Riley.   

Abstract

Bacteremia caused by Clostridium difficile is rare. In this report, we describe a case of C. difficile bacteremia caused by an unusual strain of C. difficile. The isolate contained neither toxin A nor B genes, however, binary toxin genes were present (tcdA(-), tcdB(-), cdtA(+), cdtB(+)) and a 7.2-kb element unrelated to the PaLoc was found inserted within the PaLoc integration site. The clinical relevance of the isolate could not be determined.

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Year:  2009        PMID： 19723585     DOI： 10.1016/j.anaerobe.2009.08.006

Source DB:  PubMed          Journal:  Anaerobe        ISSN： 1075-9964            Impact factor:   3.331


  18 in total

Review 1.  An Update on Clostridium difficile Toxinotyping.

Authors:  Maja Rupnik; Sandra Janezic
Journal:  J Clin Microbiol       Date:  2015-10-28       Impact factor: 5.948

Review 2.  Diagnosis of Clostridium difficile infection: an ongoing conundrum for clinicians and for clinical laboratories.

Authors:  Carey-Ann D Burnham; Karen C Carroll
Journal:  Clin Microbiol Rev       Date:  2013-07       Impact factor: 26.132

Review 3.  The role of toxins in Clostridium difficile infection.

Authors:  Ramyavardhanee Chandrasekaran; D Borden Lacy
Journal:  FEMS Microbiol Rev       Date:  2017-11-01       Impact factor: 16.408

4.  A new type of toxin A-negative, toxin B-positive Clostridium difficile strain lacking a complete tcdA gene.

Authors:  Sandra Janezic; Mercedes Marín; Adoración Martín; Maja Rupnik
Journal:  J Clin Microbiol       Date:  2014-11-26       Impact factor: 5.948

5.  Two case reports of Clostridium difficile bacteremia, one with the epidemic NAP-1 strain.

Authors:  J Hemminger; J-M Balada-Llasat; M Raczkowski; M Buckosh; P Pancholi
Journal:  Infection       Date:  2011-04-21       Impact factor: 3.553

Review 6.  Diversity and Evolution in the Genome of Clostridium difficile.

Authors:  Daniel R Knight; Briony Elliott; Barbara J Chang; Timothy T Perkins; Thomas V Riley
Journal:  Clin Microbiol Rev       Date:  2015-07       Impact factor: 26.132

7.  Macro and micro diversity of Clostridium difficile isolates from diverse sources and geographical locations.

Authors:  Richard A Stabler; Lisa F Dawson; Esmeralda Valiente; Michelle D Cairns; Melissa J Martin; Elizabeth H Donahue; Thomas V Riley; J Glenn Songer; Ed J Kuijper; Kate E Dingle; Brendan W Wren
Journal:  PLoS One       Date:  2012-03-02       Impact factor: 3.240

Review 8.  Clostridium difficile bacteremia, Taiwan.

Authors:  Nan-Yao Lee; Yu-Tsung Huang; Po-Ren Hsueh; Wen-Chien Ko
Journal:  Emerg Infect Dis       Date:  2010-08       Impact factor: 6.883

9.  Molecular epidemiology of Clostridium difficile at a medical center in Taiwan: persistence of genetically clustering of A⁻B⁺ isolates and increase of A⁺B⁺ isolates.

Authors:  Ju-Hsin Chia; Hsin-Chih Lai; Lin-Hui Su; An-Jing Kuo; Tsu-Lan Wu
Journal:  PLoS One       Date:  2013-10-07       Impact factor: 3.240

10.  Evolutionary history of the Clostridium difficile pathogenicity locus.

Authors:  Kate E Dingle; Briony Elliott; Esther Robinson; David Griffiths; David W Eyre; Nicole Stoesser; Alison Vaughan; Tanya Golubchik; Warren N Fawley; Mark H Wilcox; Timothy E Peto; A Sarah Walker; Thomas V Riley; Derrick W Crook; Xavier Didelot
Journal:  Genome Biol Evol       Date:  2014-01       Impact factor: 3.416
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