Literature DB >> 19723554

Estimating tar and nicotine exposure: human smoking versus machine generated smoke yields.

F K St Charles1, A A Kabbani, M F Borgerding.   

Abstract

OBJECTIVE: Determine human smoked (HS) cigarette yields of tar and nicotine for smokers using their own brand in their everyday environment.
METHOD: A robust, filter analysis method was used to estimate the tar and nicotine yields for 784 subjects. Seventeen brands were chosen to represent a wide range of styles: 85 and 100 mm lengths; menthol and non-menthol; 17, 23, and 25 mm circumference; with tar yields [Federal Trade Commission (FTC) method] ranging from 1 to 18 mg. Tar bands chosen corresponded to yields of 1-3 mg, 4-6 mg, 7-12 mg, and 13+ mg.
RESULTS: A significant difference (p<0.0001) in HS yields of tar and nicotine between tar bands was found. Machine-smoked yields were reasonable predictors of the HS yields for groups of subjects, but the relationship was neither exact nor linear. Neither the FTC, the Massachusetts (MA) nor the Canadian Intensive (CI) machine-smoking methods accurately reflect the HS yields across all brands. The FTC method was closest for the 7-12 mg and 13+ mg products and the MA method was closest for the 1-3mg products. The HS yields for the 4-6 mg products were approximately midway between the FTC and the MA yields. HS nicotine yields corresponded well with published urinary and plasma nicotine biomarker studies. 2009 Elsevier Inc. All rights reserved.

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Year:  2009        PMID: 19723554     DOI: 10.1016/j.yrtph.2009.08.011

Source DB:  PubMed          Journal:  Regul Toxicol Pharmacol        ISSN: 0273-2300            Impact factor:   3.271


  9 in total

Review 1.  Scientific assessment of the use of sugars as cigarette tobacco ingredients: a review of published and other publicly available studies.

Authors:  Ewald Roemer; Matthias K Schorp; Jean-Jacques Piadé; Jeffrey I Seeman; Donald E Leyden; Hans-Juergen Haussmann
Journal:  Crit Rev Toxicol       Date:  2012-01-21       Impact factor: 5.635

2.  Measurement of urinary Benzo[a]pyrene tetrols and their relationship to other polycyclic aromatic hydrocarbon metabolites and cotinine in humans.

Authors:  Donald C Hilton; Debra A Trinidad; Kendra Hubbard; Zheng Li; Andreas Sjödin
Journal:  Chemosphere       Date:  2017-09-18       Impact factor: 7.086

3.  Assessing Discrimination of Nicotine in Humans Via Cigarette Smoking.

Authors:  Kenneth A Perkins; Nicole Kunkle; Valerie C Michael; Joshua L Karelitz; Eric C Donny
Journal:  Nicotine Tob Res       Date:  2016-03-24       Impact factor: 4.244

4.  A High Throughput Method for Estimating Mouth-Level Intake of Mainstream Cigarette Smoke.

Authors:  Xizheng Yan; Liqin Zhang; Bryan A Hearn; Liza Valentín-Blasini; Gregory M Polzin; Clifford H Watson
Journal:  Nicotine Tob Res       Date:  2015-02-02       Impact factor: 4.244

5.  Mouth Level Exposure and Similarity to Machine-smoked Constituent Yields.

Authors:  Kia J Jackson; Megan J Schroeder; Allison C Hoffman
Journal:  Tob Regul Sci       Date:  2016-01-01

6.  Threshold dose for discrimination of nicotine via cigarette smoking.

Authors:  Kenneth A Perkins; Nicole Kunkle; Joshua L Karelitz; Valerie C Michael; Eric C Donny
Journal:  Psychopharmacology (Berl)       Date:  2016-04-02       Impact factor: 4.530

7.  Sex Differences in Subjective Responses To Moderate Versus Very Low Nicotine Content Cigarettes.

Authors:  Kenneth A Perkins; Joshua L Karelitz; Nicole Kunkle
Journal:  Nicotine Tob Res       Date:  2018-09-04       Impact factor: 4.244

8.  Use of illicit drugs, alcohol and tobacco in Spain and Portugal during the COVID-19 crisis in 2020 as measured by wastewater-based epidemiology.

Authors:  Andrea Estévez-Danta; Lubertus Bijlsma; Ricardo Capela; Rafael Cela; Alberto Celma; Félix Hernández; Unax Lertxundi; João Matias; Rosa Montes; Gorka Orive; Ailette Prieto; Miguel M Santos; Rosario Rodil; José Benito Quintana
Journal:  Sci Total Environ       Date:  2022-05-04       Impact factor: 10.753

9.  Using Monte Carlo simulation to assess variability and uncertainty of tobacco consumption in a city by sewage epidemiology.

Authors:  De-Gao Wang; Qian-Qian Dong; Juan Du; Shuo Yang; Yun-Jie Zhang; Guang-Shui Na; Stuart G Ferguson; Zhuang Wang; Tong Zheng
Journal:  BMJ Open       Date:  2016-02-17       Impact factor: 2.692

  9 in total

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