Literature DB >> 19722661

Gold nanoparticles functionalized with gadolinium chelates as high-relaxivity MRI contrast agents.

Loïck Moriggi1, Caroline Cannizzo, Eddy Dumas, Cédric R Mayer, Alexey Ulianov, Lothar Helm.   

Abstract

Water-dispersible gold nanoparticles functionalized with paramagnetic gadolinium have been fully characterized, and the NMRD profiles show very high relaxivities up to 1.5 T. Characterization using TEM images and dynamic light scattering indicate a particle size distribution from 2 to 15 nm. The gold cores of the nanoparticles do not contribute significantly to the overall magnetic moment.

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Year:  2009        PMID： 19722661     DOI： 10.1021/ja904094t

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  21 in total

1.  Strategies for the preparation of bifunctional gadolinium(III) chelators.

Authors:  Luca Frullano; Peter Caravan
Journal:  Curr Org Synth       Date:  2011-08-01       Impact factor: 1.975

2.  High relaxivity Gd(III)-DNA gold nanostars: investigation of shape effects on proton relaxation.

Authors:  Matthew W Rotz; Kayla S B Culver; Giacomo Parigi; Keith W MacRenaris; Claudio Luchinat; Teri W Odom; Thomas J Meade
Journal:  ACS Nano       Date:  2015-03-24       Impact factor: 15.881

3.  Multimodal gadolinium-enriched DNA-gold nanoparticle conjugates for cellular imaging.

Authors:  Ying Song; Xiaoyang Xu; Keith W MacRenaris; Xue-Qing Zhang; Chad A Mirkin; Thomas J Meade
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336

4.  Enhanced MRI relaxivity of Gd(3+) -based contrast agents geometrically confined within porous nanoconstructs.

Authors:  Richa Sethi; Jeyarama S Ananta; Christof Karmonik; Meng Zhong; Steve H Fung; Xuewu Liu; King Li; Mauro Ferrari; Lon J Wilson; Paolo Decuzzi
Journal:  Contrast Media Mol Imaging       Date:  2012 Nov-Dec       Impact factor: 3.161

5.  A Markedly Improved Synthetic Approach for the Preparation of Multifunctional Au-DNA Nanoparticle Conjugates Modified with Optical and MR Imaging Probes.

Authors:  Matthew W Rotz; Robert J Holbrook; Keith W MacRenaris; Thomas J Meade
Journal:  Bioconjug Chem       Date:  2018-10-10       Impact factor: 4.774

6.  Gadolinium-conjugated gold nanoshells for multimodal diagnostic imaging and photothermal cancer therapy.

Authors:  Andrew J Coughlin; Jeyarama S Ananta; Nanfu Deng; Irina V Larina; Paolo Decuzzi; Jennifer L West
Journal:  Small       Date:  2013-09-23       Impact factor: 13.281

7.  Gd@C82 metallofullerenes for neutron capture therapy-fullerene solubilization by poly(ethylene glycol)-block-poly(2-(N, N-diethylamino)ethyl methacrylate) and resultant efficacy in vitro.

Authors:  Yukichi Horiguchi; Shinpei Kudo; Yukio Nagasaki
Journal:  Sci Technol Adv Mater       Date:  2011-07-07       Impact factor: 8.090

Review 8.  Engineering Gd-loaded nanoparticles to enhance MRI sensitivity via T(1) shortening.

Authors:  Michael A Bruckman; Xin Yu; Nicole F Steinmetz
Journal:  Nanotechnology       Date:  2013-10-24       Impact factor: 3.874

9.  Towards clinically translatable in vivo nanodiagnostics.

Authors:  Seung-Min Park; Amin Aalipour; Ophir Vermesh; Jung Ho Yu; Sanjiv S Gambhir
Journal:  Nat Rev Mater       Date:  2017-05-03       Impact factor: 66.308

10.  Mechanisms of Gadographene-Mediated Proton Spin Relaxation.

Authors:  Andy H Hung; Matthew C Duch; Giacomo Parigi; Matthew W Rotz; Lisa M Manus; Daniel J Mastarone; Kevin T Dam; Colton C Gits; Keith W Macrenaris; Claudio Luchinat; Mark C Hersam; Thomas J Meade
Journal:  J Phys Chem C Nanomater Interfaces       Date:  2013-08-08       Impact factor: 4.126
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