Literature DB >> 19684597

Isolation of deletion alleles by G4 DNA-induced mutagenesis.

Daphne B Pontier1, Evelien Kruisselbrink, Victor Guryev, Marcel Tijsterman.   

Abstract

Metazoan genomes contain thousands of sequence tracts that match the guanine-quadruplex (G4) DNA signature G(3)N(x)G(3)N(x)G(3)N(x)G(3), a motif that is intrinsically mutagenic, probably because it can form secondary structures during DNA replication. Here we show how and to what extent this feature can be used to generate deletion alleles of many Caenorhabditis elegans genes.

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Year:  2009        PMID： 19684597     DOI： 10.1038/nmeth.1362

Source DB:  PubMed          Journal:  Nat Methods        ISSN： 1548-7091            Impact factor:   28.547


  10 in total

1.  Helix formation by guanylic acid.

Authors:  M GELLERT; M N LIPSETT; D R DAVIES
Journal:  Proc Natl Acad Sci U S A       Date:  1962-12-15       Impact factor: 11.205

2.  Dynamic roles for G4 DNA in the biology of eukaryotic cells.

Authors:  Nancy Maizels
Journal:  Nat Struct Mol Biol       Date:  2006-12       Impact factor: 15.369

3.  Replication stalling at unstable inverted repeats: interplay between DNA hairpins and fork stabilizing proteins.

Authors:  Irina Voineagu; Vidhya Narayanan; Kirill S Lobachev; Sergei M Mirkin
Journal:  Proc Natl Acad Sci U S A       Date:  2008-07-15       Impact factor: 11.205

4.  Characterization of mutations induced by ethyl methanesulfonate, UV, and trimethylpsoralen in the nematode Caenorhabditis elegans.

Authors:  K Gengyo-Ando; S Mitani
Journal:  Biochem Biophys Res Commun       Date:  2000-03-05       Impact factor: 3.575

5.  Disruption of dog-1 in Caenorhabditis elegans triggers deletions upstream of guanine-rich DNA.

Authors:  Iris Cheung; Michael Schertzer; Ann Rose; Peter M Lansdorp
Journal:  Nat Genet       Date:  2002-07-08       Impact factor: 38.330

6.  G4-forming sequences in the non-transcribed DNA strand pose blocks to T7 RNA polymerase and mammalian RNA polymerase II.

Authors:  Silvia Tornaletti; Shaun Park-Snyder; Philip C Hanawalt
Journal:  J Biol Chem       Date:  2008-02-20       Impact factor: 5.157

7.  Mutagenic capacity of endogenous G4 DNA underlies genome instability in FANCJ-defective C. elegans.

Authors:  Evelien Kruisselbrink; Victor Guryev; Karin Brouwer; Daphne B Pontier; Edwin Cuppen; Marcel Tijsterman
Journal:  Curr Biol       Date:  2008-06-05       Impact factor: 10.834

8.  Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis.

Authors:  D Sen; W Gilbert
Journal:  Nature       Date:  1988-07-28       Impact factor: 49.962

9.  DOG-1 is the Caenorhabditis elegans BRIP1/FANCJ homologue and functions in interstrand cross-link repair.

Authors:  Jillian L Youds; Louise J Barber; Jordan D Ward; Spencer J Collis; Nigel J O'Neil; Simon J Boulton; Ann M Rose
Journal:  Mol Cell Biol       Date:  2007-12-17       Impact factor: 4.272

10.  Improved detection of small deletions in complex pools of DNA.

Authors:  Mark Edgley; Anil D'Souza; Gary Moulder; Sheldon McKay; Bin Shen; Erin Gilchrist; Donald Moerman; Robert Barstead
Journal:  Nucleic Acids Res       Date:  2002-06-15       Impact factor: 16.971
  10 in total
  12 in total

1.  Guanine Quadruplex DNA Regulates Gamma Radiation Response of Genome Functions in the Radioresistant Bacterium Deinococcus radiodurans.

Authors:  Shruti Mishra; Reema Chaudhary; Sudhir Singh; Swathi Kota; Hari S Misra
Journal:  J Bacteriol       Date:  2019-08-08       Impact factor: 3.490

Review 2.  From genes to function: the C. elegans genetic toolbox.

Authors:  Thomas Boulin; Oliver Hobert
Journal:  Wiley Interdiscip Rev Dev Biol       Date:  2011-11-28       Impact factor: 5.814

3.  DNA secondary structures and epigenetic determinants of cancer genome evolution.

Authors:  Subhajyoti De; Franziska Michor
Journal:  Nat Struct Mol Biol       Date:  2011-07-03       Impact factor: 15.369

Review 4.  Forward and reverse mutagenesis in C. elegans.

Authors:  Lena M Kutscher; Shai Shaham
Journal:  WormBook       Date:  2014-01-17

Review 5.  What does physics have to do with cancer?

Authors:  Franziska Michor; Jan Liphardt; Mauro Ferrari; Jonathan Widom
Journal:  Nat Rev Cancer       Date:  2011-08-18       Impact factor: 60.716

6.  Targeted gene deletions in C. elegans using transposon excision.

Authors:  Christian Frøkjaer-Jensen; M Wayne Davis; Gunther Hollopeter; Jon Taylor; Todd W Harris; Paola Nix; Rachel Lofgren; Michael Prestgard-Duke; Michael Bastiani; Donald G Moerman; Erik M Jorgensen
Journal:  Nat Methods       Date:  2010-04-25       Impact factor: 28.547

7.  How long is too long? Effects of loop size on G-quadruplex stability.

Authors:  Aurore Guédin; Julien Gros; Patrizia Alberti; Jean-Louis Mergny
Journal:  Nucleic Acids Res       Date:  2010-07-26       Impact factor: 16.971

8.  A non-canonical DNA structure is a binding motif for the transcription factor SP1 in vitro.

Authors:  Eun-Ang Raiber; Ramon Kranaster; Enid Lam; Mehran Nikan; Shankar Balasubramanian
Journal:  Nucleic Acids Res       Date:  2011-10-22       Impact factor: 16.971

9.  Spectrum of variations in dog-1/FANCJ and mdf-1/MAD1 defective Caenorhabditis elegans strains after long-term propagation.

Authors:  Maja Tarailo-Graovac; Tammy Wong; Zhaozhao Qin; Stephane Flibotte; Jon Taylor; Donald G Moerman; Ann M Rose; Nansheng Chen
Journal:  BMC Genomics       Date:  2015-03-18       Impact factor: 3.969

10.  CNBP Binds and Unfolds In Vitro G-Quadruplexes Formed in the SARS-CoV-2 Positive and Negative Genome Strands.

Authors:  Georgina Bezzi; Ernesto J Piga; Andrés Binolfi; Pablo Armas
Journal:  Int J Mol Sci       Date:  2021-03-05       Impact factor: 5.923
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